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Previous Volume 337:677-681 September 4, 1997 Number 10 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Yersinia pestis is the causative agent of plague, a zoonotic disease transmitted to humans through flea bites and typically characterized by the appearance of a tender and swollen lymph node, the bubo. Human-to-human transmission can occur, through either the bite of fleas (bubonic plague) or respiratory droplets, causing an overwhelming infection called pneumonic plague.

The last plague pandemic began in Hong Kong in 1894 and spread throughout the world, establishing many endemic foci. Antibiotics and enforcement of public health measures significantly decreased the morbidity and mortality associated with the disease but did not allow its eradication. In fact, plague . . . [Full Text of this Article]

Methods

Patient and Strains

Mediums and Resistance Studies

Nucleic-Acid Techniques

Results

Antibiotic Resistance of Y. pestis 17/95

Characterization of Plasmid pIP1202

Analysis of Plasmid DNA

Discussion

Source Information

From the National Reference Center for Antibiotics and the Unité des Agents Antibactériens (M.G., G.G., P.C.) and the National Reference Laboratory–World Health Organization Collaborating Center for Yersinia (A.G., E.C.), Institut Pasteur, Paris; and the Plague Central Laboratory, Institut Pasteur, Antananarivo, Madagascar (B.R., S.C.).

Address reprint requests to Dr. Carniel at the National Reference Laboratory–WHO Collaborating Center for Yersinia, Institut Pasteur, 28 rue du Dr. Roux, 75724 Paris CEDEX 15, France.

References

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