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Case Records of the Massachusetts General Hospital
Weekly Clinicopathological Exercises
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Volume 337:770-777 September 11, 1997 Number 11
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Case 28-1997— A 67-Year-Old Woman with Increasing Neurologic Deficits and a History of Breast and Ovarian Cancer
Judy E. Garber, and Esther Oliva

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Presentation of Case

A 67-year-old woman was admitted to the hospital because of nausea and increasing confusion.

The patient had undergone excision and radiation therapy for carcinoma of the left breast 13 years before admission and for carcinoma of the right breast 7 years later. Eight years before admission, she had a hysterectomy with bilateral salpingo-oophorectomy for ovarian carcinoma. Two years before admission, a sigmoid resection with a colostomy was performed because of recurrent tumor. The patient had undergone multiple chemotherapy regimens, including cyclophosphamide, methotrexate, and fluorouracil for breast cancer and paclitaxel, cisplatin, and carboplatin for ovarian cancer. Eighteen days before the current . . . [Full Text of this Article]

Differential Diagnosis

Clinical Diagnosis

Dr. Judy E. Garber's Diagnoses

Pathological Discussion

Anatomical Diagnoses

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