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Correspondence
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Volume 337:863 September 18, 1997 Number 12
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Maternal and Umbilical-Cord Serum Leptin Concentrations in Normal, Full-Term Pregnancies

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 by Considine, R. V.
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To the Editor: Serum concentrations of leptin, a hormonal product of adipose tissue, correlate closely with body-mass index and adipose-tissue mass in adults1 and children,2 but these relations have not been studied in pregnant women and their neonates.

We measured serum leptin immediately after delivery in 76 normal women (mean [±SD] age, 28±4 years), with singleton pregnancies and in their newborn infants. All the women had normal, full-term pregnancies and normal vaginal deliveries. Women who smoked more than nine cigarettes per day or who had perinatal obstetrical complications were excluded. Serum concentrations of leptin, insulin, and insulin-like growth factor I . . . [Full Text of this Article]

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