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Previous Volume 337:1159-1161 October 16, 1997 Number 16 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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In the typical two-group clinical trial with outcomes of either success or failure, investigators are interested in finding out whether an innovative treatment, T, reduces the frequency of failure relative to standard therapy, S. If p_T and p_S are used to represent the respective frequencies, this question can be answered by testing the null hypothesis of equal efficacy, H₀: p_T = p_S, against the alternative hypothesis of superiority, H_A: p_T < p_S. If the null hypothesis can be rejected in favor of the alternative hypothesis, we conclude that the new therapy is superior to standard therapy. . . . [Full Text of this Article]

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Thrombolytic Therapy for Myocardial Infarction
Frei S., Brophy J., Andreotti F., Thron C. D., Topol E. J., Califf R. M., Wilcox R., The GUSTO III Steering Committee , Van de Werf F., The COBALT Investigators , Ware J. H., Antman E. M.
Extract | Full Text  
N Engl J Med 1998; 338:545-548, Feb 19, 1998. Correspondence

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