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Volume 337:1178-1179 October 16, 1997 Number 16
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A Commotion in the Blood: Life, death, and the immune system

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By Stephen S. Hall. 544 pp. New York, Henry Holt, 1997. $30. ISBN 0-8050-3796-9.

About 25 years ago, an irreverent wag used "lymphodrek" to refer to the mysterious factors released by cultured lymphocytes or macrophages that could activate, attract, or inhibit other mononuclear leukocytes. These enigmatic phenomena seemed to depend largely on ingenious experimental conditions that outsiders found incomprehensible. Moreover, no sooner did one laboratory describe an activity — invariably with an acronym — than another reported a different acronym with similar effects. Who could have predicted that this Babel would yield not only numerous potent lymphokines but also molecules with the power to incite guile, greed, and pitiless malevolence in researchers?

Stephen Hall's . . . [Full Text of this Article]




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