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Correspondence
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Volume 337:1245-1247 October 23, 1997 Number 17
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DNA Testing to Refute a Diagnosis of Cancer

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 by Schömig, A.
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To the Editor: The use of DNA testing in forensics has been widely publicized. We used DNA testing to determine that a pathological diagnosis of cancer was based on extraneous tissue and thereby avoided unnecessary treatment. A 44-year-old woman underwent a uterine myomectomy and had postoperative complications resulting in ascites and right pleural effusion two weeks later. The pleural effusion filled the right chest cavity and rapidly recurred after thoracentesis. Thoracoscopy was performed for pleurodesis. Pleural biopsy showed multiple fragments of mesothelial-cell proliferation and a single, isolated, 1-mm fragment of adenocarcinoma (Figure 1A and Figure 1B). The serum . . . [Full Text of this Article]

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