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Volume 337:1563 November 20, 1997 Number 21
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Cancer of the Nervous System

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Edited by Peter M. Black and Jay S. Loeffler. 935 pp., illustrated. Cambridge, Mass., Blackwell Science, 1997. $250. ISBN 0-86542-384-9.

Cancer can involve the nervous system in many ways. Metastases to brain parenchyma occur in 20 to 40 percent of patients with cancer, spinal cord compressions are diagnosed in over 5 percent of patients with cancer, and leptomeningeal involvement is seen in approximately 30 percent of patients with lung cancer and 5 percent of patients with breast cancer. Primary tumors of the brain, spinal cord, and peripheral nerves are far less common but comprise a heterogeneous group of tumors with vastly differing prognoses and appropriate therapies. In addition, clinicians must be familiar with paraneoplastic syndromes that infrequently result in devastating . . . [Full Text of this Article]




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