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Case Records of the Massachusetts General Hospital
Weekly Clinicopathological Exercises
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Volume 337:1612-1619 November 27, 1997 Number 22
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Case 37-1997— A 59-Year-Old Man with Anorexia, Weight Loss, and a Mediastinal Mass
Richard P. MacDermott, and Fiona M. Graeme-Cook

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Presentation of Case

A 59-year-old man was admitted to the clinic because of anorexia, fatigue, weight loss, and a mediastinal mass.

The patient had been well until two years earlier, when his appetite and taste sensation decreased, with an ultimate loss of 16 kg in weight. He felt tired but continued to work as an automobile mechanic. He occasionally had mild headaches and dyspnea. An evaluation elsewhere showed a mediastinal mass; a biopsy revealed only fibrofatty tissue. Mild anemia, hypoalbuminemia, and a polyclonal gammopathy were detected. The patient had visited a Brazilian city for a month on four occasions during the preceding six . . . [Full Text of this Article]

Differential Diagnosis

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Dr. Richard P. MacDermott's Diagnosis

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