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Previous Volume 337:1686-1687 December 4, 1997 Number 23 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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As life expectancy continues to increase, women will soon be postmenopausal for one third of their lives. The human and economic costs of this increased longevity in an estrogen-deficient state are substantial. They include a projected increase in cardiovascular events, the leading cause of death among postmenopausal women, and in osteoporotic hip fractures, which are associated with a 20 percent mortality rate within the first year. However, despite the well-established efficacy of estrogens in protecting women against cardiovascular disease and maintaining bone density and reducing fractures, less than one fifth of postmenopausal women ever take them.¹ Furthermore, the proportion who . . . [Full Text of this Article]

References

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• Danilovich, N., Babu, P. S., Xing, W., Gerdes, M., Krishnamurthy, H., Sairam, M. R. (2000). Estrogen Deficiency, Obesity, and Skeletal Abnormalities in Follicle-Stimulating Hormone Receptor Knockout (FORKO) Female Mice. Endocrinology 141: 4295-4308 [Abstract] [Full Text]  
• Pfeilschifter, J., Diel, I. J. (2000). Osteoporosis Due to Cancer Treatment: Pathogenesis and Management. JCO 18: 1570-1593 [Abstract] [Full Text]