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Previous Volume 337:1696-1697 December 4, 1997 Number 23 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Gordin et al. (July 31 issue)¹ conclude that isoniazid prophylaxis is not useful in patients with human immunodeficiency virus (HIV) infection who have anergy and multiple risk factors for latent tuberculosis. We are concerned about the validity and generalizability of this conclusion.

First, we doubt that the patients included in the study by Gordin et al. were highly representative of patients who are truly at high risk for tuberculosis. The incidence of tuberculosis in the placebo group was only 0.9 per 100 person-years, which is very close to the overall incidence of tuberculosis among HIV-infected persons in . . . [Full Text of this Article]

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