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Correspondence
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Volume 337:1921-1922 December 25, 1997 Number 26
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Management of Hepatic Encephalopathy

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 by Adachi, J. D.
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 by Riordan, S. M.
To the Editor: In their review, Riordan and Williams (Aug. 14 issue)1 state that protein restriction is a well-documented therapy for hepatic encephalopathy and imply that a high dietary protein intake is a common cause of hepatic encephalopathy in patients with liver cirrhosis. To our knowledge, scientific proof of the benefit of protein restriction is lacking, and there are no controlled studies of protein restriction. The authors refer to a chapter in a book2 and an experimental study in dogs.3 They recommend minimal daily protein intakes of 0.8 to 1.0 g per kilogram of body weight to maintain nitrogen balance.

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