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Correspondence
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Volume 337:203-204 July 17, 1997 Number 3
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More on Continuous-Infusion Acyclovir for Severe Varicella

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To the Editor: In their letter reporting the use of a continuous infusion of acyclovir to treat severe hemorrhagic varicella (March 6 issue),1 Kakinuma and Itoh describe serologically confirmed infection with varicella-zoster virus in a patient with leukemia who had no response to the conventional regimen of therapy. However, the conventional-regimen dose of 250 mg of intravenous acyclovir every eight hours that was used in this 40-year-old woman is well below the dose of acyclovir recommended to treat varicella-zoster virus infection in immunocompromised patients -- namely, 10 mg per kilogram of body weight every eight hours.2

From the stated continuous-infusion . . . [Full Text of this Article]

References


Related Letters:

A Continuous Infusion of Acyclovir for Severe Hemorrhagic Varicella
Kakinuma H., Itoh E.
Extract | Full Text  
N Engl J Med 1997; 336:732-733, Mar 6, 1997. Correspondence



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