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Previous Volume 337:237-240 July 24, 1997 Number 4 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Invasive diagnostic or therapeutic procedures may be a route for the transmission of the hepatitis C virus (HCV).^1,2,3,4,5 In a study of patients in a gastrointestinal-disease unit, endoscopic biopsies were found to be an independent risk factor for HCV infection.⁶ We report the transmission of HCV during colonoscopy from a person known to have HCV infection to two other patients. The patient-to-patient transmission was ascertained by sequencing the nucleotides in the various HCV isolates.

Case Report

A 55-year-old man (Patient 1) and his 54-year-old wife (Patient 2) were referred in October 1995. In June 1995, both had had hepatitis-like illnesses, with nausea, . . . [Full Text of this Article]

Methods

Detection and Titration of HCV RNA

HCV Genotyping and Nucleotide Sequencing

Results

Detection and Quantitation of HCV RNA

Genotyping and Sequencing of HCV

Procedures Used for Colonoscopy, Disinfection, and Anesthesia

Discussion

Source Information

From the Service d'Hépato-Gastroentérologie (J.-P.B., L.C., H.H., C.D., M.-A.B., P.G.), the Laboratoire de Microbiologie (V.V., B.R., A.L.), the Etablissement de Transfusion Sanguine (C.B.), the Laboratoire Commun de Biologie Moléculaire (N.M.), and the Laboratoire de Pathologie Cellulaire et Moléculaire en Nutrition (J.-P.B., I.G., M.-A.B., P.G.), Faculté de Médecine et Centre Hospitalier Universitaire de Nancy, Vandoeuvre, France.

Address reprint requests to Dr. Bronowicki at the Service d'Hépato-Gastroentérologie, CHU de Nancy, 54500 Vandoeuvre, France.

References

Related Letters:

Transmission of Hepatitis C Virus during Colonoscopy
Kozarek R. A., Bronowicki J.-P., Bigard M.-A.
Extract | Full Text  
N Engl J Med 1997; 337:1848-1849, Dec 18, 1997. Correspondence

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