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Correspondence
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Volume 337:499-501 August 14, 1997 Number 7
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Postexposure Treatment of HIV

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 by Katz, M. H.
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To the Editor: Katz and Gerberding (April 10 issue)1 raise questions about public health policy related to the costs of antiretroviral therapy given immediately after an exposure to the human immunodeficiency virus (HIV) to prevent seroconversion in persons at high risk for HIV infection. Using their data and the techniques of decision analysis, we examined the cost effectiveness of prophylaxis against HIV.

We compared no prophylaxis with prophylaxis with zidovudine; zidovudine and lamivudine; and zidovudine, lamivudine, and indinavir — all given for four weeks at average wholesale costs of $260, $469, and $931, respectively. The cost of initial and follow-up . . . [Full Text of this Article]

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