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Correspondence
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Volume 337:641-642 August 28, 1997 Number 9
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Interferon Alfa Treatment of a Patient with Eosinophilic Cellulitis and HIV Infection

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To the Editor: In June 1994, a 36-year-old man with human immunodeficiency virus (HIV) infection who was otherwise healthy began to have recurrent swellings of the soft tissue (>20 per month) in various body regions that lasted two to three days and resembled acute cellulitis. This was accompanied by peripheral-blood eosinophilia (32 percent eosinophils). Light microscopy revealed tissue eosinophilia and characteristic "flame figures." Eosinophilic cellulitis was diagnosed.

In October 1994, we initiated therapy with systemic corticosteroids and dapsone, and the patient did well, with two to three swellings per month. In July 1995, he again noticed increasing swellings and was . . . [Full Text of this Article]

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