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Previous Volume 338:1461-1463 May 14, 1998 Number 20 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Epstein–Barr virus (EBV), a B-lymphotropic herpesvirus carried by almost everyone as a lifelong asymptomatic infection, is implicated in the pathogenesis of at least three malignant disorders of B cells.¹ One is Burkitt's lymphoma, which in its endemic form in equatorial Africa almost always contains the virus. A rare sporadic form of Burkitt's lymphoma that occurs in Western countries contains the virus in 10 to 20 percent of cases. The second B-cell tumor linked to EBV is classic Hodgkin's disease,² which is associated with the virus in 40 percent of the cases in the West and in more than 80 percent . . . [Full Text of this Article]

References

This article has been cited by other articles:

• Chuang, H.-C., Lay, J.-D., Chuang, S.-E., Hsieh, W.-C., Chang, Y., Su, I.-J. (2007). Epstein-Barr Virus (EBV) Latent Membrane Protein-1 Down-Regulates Tumor Necrosis Factor-{alpha} (TNF-{alpha}) Receptor-1 and Confers Resistance to TNF-{alpha}-Induced Apoptosis in T Cells: Implication for the Progression to T-Cell Lymphoma in EBV-Associated Hemophagocytic Syndrome. Am. J. Pathol. 170: 1607-1617 [Abstract] [Full Text]  
• Chuang, H.-C., Lay, J.-D., Hsieh, W.-C., Wang, H.-C., Chang, Y., Chuang, S.-E., Su, I.-J. (2005). Epstein-Barr virus LMP1 inhibits the expression of SAP gene and upregulates Th1 cytokines in the pathogenesis of hemophagocytic syndrome. Blood 106: 3090-3096 [Abstract] [Full Text]