How many medications are optimal for a patient with multiplemedical problems? Prescribing too many increases the likelihoodof side effects, drug interactions, and poor compliance. Prescribingtoo few may leave important conditions or symptoms untreated.Of course, there is no correct answer to such a simplistic question.However, in a provocative article in this issue of the Journal,Redelmeier and colleagues argue that physicians frequently undertreatpatients with multiple chronic medical conditions.1
Redelmeier et al. conducted a clever study of all residentsof Ontario, Canada, who were eligible to receive prescriptionmedications free of charge as part of the . . . [Full Text of this Article]
Huang, E. S., Brown, S. E.S., Thakur, N., Carlisle, L., Foley, E., Ewigman, B., Meltzer, D. O.
(2009). Racial/Ethnic Differences in Concerns About Current and Future Medications Among Patients With Type 2 Diabetes. Diabetes Care
32: 311-316
[Abstract][Full Text]
Austin, R. P.
(2006). Polypharmacy as a Risk Factor in the Treatment of Type 2 Diabetes. Diabetes Spectr.
19: 13-16
[Full Text]
Wang, P. S., Avorn, J., Brookhart, M. A., Mogun, H., Schneeweiss, S., Fischer, M. A., Glynn, R. J.
(2005). Effects of Noncardiovascular Comorbidities on Antihypertensive Use in Elderly Hypertensives. Hypertension
46: 273-279
[Abstract][Full Text]
McAlister, F. A., Stewart, S., Ferrua, S., McMurray, J. J.J.V.
(2004). Multidisciplinary strategies for the management of heart failure patients at high risk for admission: A systematic review of randomized trials. J Am Coll Cardiol
44: 810-819
[Abstract][Full Text]
Hilliard, A. A., Weinberger, S. E., Tierney, L. M. Jr., Midthun, D. E., Saint, S.
(2004). Occam's Razor versus Saint's Triad. NEJM
350: 599-603
[Full Text]
Rochon, P. A., Gurwitz, J. H.
(1999). Prescribing for Seniors: Neither Too Much nor Too Little. JAMA
282: 113-115
[Full Text]
Fisher, E. S., Welch, H. G.
(1999). Avoiding the Unintended Consequences of Growth in Medical Care: How Might More Be Worse?. JAMA
281: 446-453
[Abstract][Full Text]
Kent, D. M., Hayward, R., Rubins, H. B., Friedman, E. A., Poses, R. M., Redelmeier, D. A., Tan, S. H., Booth, G. L.
(1998). Treating Unrelated Disorders in Patients with Chronic Disease. NEJM
339: 926-928
[Full Text]
Richards, T.
(1998). Disease management in Europe. BMJ
317: 426-427
[Full Text]