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Previous Volume 338:1774-1775 June 11, 1998 Number 24 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: From May 1993 through February 1998, the Food and Drug Administration (FDA) received reports of 43 patients in the United States who had spinal or epidural hematoma or bleeding after receiving the low-molecular-weight heparin enoxaparin (Lovenox, Rhône–Poulenc Rorer Pharmaceuticals). Emergency decompressive laminectomy to evacuate the hematoma was performed in 28 patients, and permanent paraplegia, often with a delay in diagnosis or surgical treatment, occurred in 16.

Of the 37 patients whose sex was reported, 29 (78 percent) were women. The median age was 75 years (range, 28 to 90). Three persons had histories of ankylosing spondylitis or . . . [Full Text of this Article]

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