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A 53-year-old man with cardiac amyloidosis was admitted to the hospital because of hemoptysis and a pulmonary lesion.
The patient had first been seen at this hospital four years earlier because of atrial fibrillation, congestive heart failure, and an embolic stroke. Microscopical examination of a specimen from a right ventricular endomyocardial biopsy showed amyloid believed to be related to transthyretin (prealbumin), a finding indicative of familial amyloidosis. A coronary angiographic study revealed minimal atherosclerosis. There was moderate global and inferior hypokinesis, with severe mitral regurgitation. Symptoms were well controlled with colchicine, furosemide, warfarin, and propranolol.
Twenty months before admission, the
Differential Diagnosis
Clinical Diagnoses
Dr. John L. Berk's Diagnosis
Pathological Discussion
Anatomical Diagnoses
Addendum
References
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