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Correspondence
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Volume 338:1924-1925 June 25, 1998 Number 26
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The Response of Early Gastric Cancer to Proton-Pump Inhibitors

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To the Editor: Early diagnosis is paramount in the successful treatment of gastric cancer.1 We have found that empirical treatment with a proton-pump inhibitor can delay the diagnosis as occurred in the first patient described below, and we have also observed, by serendipity, the effect of a short course of a proton-pump inhibitor on the symptoms and endoscopic signs of early gastric cancer in another patient.

The first patient was a 41-year-old woman who was referred with a biopsy-confirmed diagnosis of gastric cancer. Four years earlier, a 1-cm gastric ulcer was seen on endoscopy, and a biopsy reportedly showed no . . . [Full Text of this Article]

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