FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |   Search Term  Advanced Search

Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe

Previous Volume 338:199-200 January 15, 1998 Number 3 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text Purchase this article Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited Related Article by Lennon, V. A. PubMed Citation

To the Editor: The chronic phase of chronic myeloid leukemia was diagnosed in a 41-year-old man and treated with interferon alfa and hydroxyurea. After four months of treatment, there was a sudden onset of high fever, severe bone pain in multiple sites, and muscle weakness. Proximal weakness was more severe in the legs than the arms. Tendon reflexes were absent bilaterally. There were no cranial-nerve dysfunctions or autonomic symptoms. Bone marrow specimens showed the characteristic features of necrosis without any sign of blast crisis (Figure 1A). At the same time, we found a high level of tumor necrosis . . . [Full Text of this Article]

References

This article has been cited by other articles:

• Elliott, M. A., Mesa, R. A., Tefferi, A., Burton, C., Azzi, A., Kerridge, I. (2002). Adverse Events after Imatinib Mesylate Therapy. NEJM 346: 712-713 [Full Text]