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Figure 1. A throbbing headache, diffuse abdominal pain, fever (temperature, 40°C [104°F]), hepatosplenomegaly, and pancytopenia (white-cell count, 3800 per cubic millimeter; hematocrit, 31 percent; and platelet count, 78,000 per cubic millimeter) developed in a 34-year-old woman several days after she had cleared rats' nests from underneath her country home. Wright's staining of her peripheral-blood smear under blue-filter microscopy showed multiple spirochetes (Panel A, x40). Staining with acridine orange (which stains bacterial and fungal RNA and single-stranded DNA bright orange and human tissue apple green) highlighted the spirochete in the blood smear (Panel B). Because of the patient's history, . . . [Full Text of this Article] |