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Figure 1. A 44-year-old woman was admitted to the medical intensive care unit with acute respiratory distress syndrome due to Streptococcus pneumoniae infection. A chest radiograph taken soon after admission revealed diffuse bilateral infiltrates (Panel A). Mechanical ventilation was instituted with a fraction of inspired oxygen of 100 percent and a positive end-expiratory pressure of 15 cm of water. Static compliance was measured at 17 ml per centimeter of water, with peak airway pressures exceeding 50 cm of water. To minimize the risk of barotrauma, the mode of ventilation was changed from intermittent mandatory ventilation to pressure-controlled ventilation with a set inspiratory . . . [Full Text of this Article] |