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Previous Volume 338:446-452 February 12, 1998 Number 7 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Classic analgesic nephropathy is a slowly progressive disease resulting from the daily use for many years of mixtures containing at least two antipyretic analgesics and usually caffeine or codeine (or both), which may lead to psychological dependence. The nephropathy is characterized by renal papillary necrosis and chronic interstitial nephritis, with an insidious progression to renal failure, sometimes in association with transitional-cell carcinoma of the uroepithelium.^1,2,3,4

In the early stages of the disease, the clinical symptoms are limited to polyuria, sometimes associated with sterile pyuria, and renal colic that is occasionally associated with acute renal failure due to bilateral obstruction of . . . [Full Text of this Article]

Is an Accurate Diagnosis of Classic Analgesic Nephropathy Possible?

Did the Banning of Phenacetin Eliminate Analgesic Nephropathy?

Does Habitual Analgesic Use Influence the Progression of Chronic Renal Disease?

Is the Prolonged Use of NSAIDs Associated with Renal Papillary Necrosis or Chronic Renal Failure?

Conclusions

Source Information

From the Department of Nephrology–Hypertension, University of Antwerp, Antwerp, Belgium.

Address reprint requests to Dr. De Broe at University Hospital Antwerp, Wilrijkstraat 10, B-2650 Antwerp (Edegem), Belgium.

References

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Analgesic Nephropathy
Michielsen P., De Schepper P., Baumeister M., Aicher B., Fox J. M., Thurlow W., De Broe M. E., Elseviers M. M.
Extract | Full Text  
N Engl J Med 1998; 339:48-50, Jul 2, 1998. Correspondence

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