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Previous Volume 338:588-590 February 26, 1998 Number 9 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Klinefelter's syndrome is a form of hypergonadotropic hypogonadism and infertility resulting from a supernumerary X chromosome (47,XXY), with an incidence of approximately 1 case in 500 phenotypic males.^1,2 Some men with Klinefelter's syndrome who have chromosomal mosaicism (46,XY/47,XXY) are fertile. Men with nonmosaic, or complete, Klinefelter's syndrome usually have azoospermia, and only a few have any spermatogenesis.^3,4

Intracytoplasmic sperm injection, in which a spermatozoon is injected into an ovum in vitro, is an effective treatment for male-factor infertility. However, the complete absence of spermatozoa presents a particular clinical challenge. Postorchitis atrophy and genetic anomalies are the main causes of nonobstructive . . . [Full Text of this Article]

Case Reports

Couple 1

Couple 2

Methods

Discussion

Source Information

From the Center for Reproductive Medicine and Infertility, Department of Obstetrics and Gynecology (G.D.P., E.S.S., L.L.V., N.Z., S.M., Z.R.), and the James Buchanan Brady Foundation, Department of Urology (P.N.S.), New York Hospital–Cornell Medical Center, New York.

Address reprint requests to Dr. Palermo at HT-336, New York Hospital, 505 E. 70th St., New York, NY 10021.

References

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