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Previous Volume 338:612-613 February 26, 1998 Number 9 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Finasteride, a 5-reductase inhibitor that slows the conversion of testosterone to dihydrotestosterone, is now a proven treatment for men who wish to reduce the genitourinary symptoms or the risk of serious complications of benign prostatic hyperplasia. In this issue of the Journal, McConnell et al.¹ report that finasteride reduced the rate of acute urinary retention by 57 percent and the need for prostatectomy by 55 percent in a large group of men with this disorder. Nevertheless, treatment with finasteride to prevent these complications may be unwarranted for most men with symptoms of this disorder. Here is why.

First, even . . . [Full Text of this Article]

References

This article has been cited by other articles:

• Fukuta, Y., Fukuda, Y., Higashino, R., Yoshida, K., Ogishima, M., Tamaki, H., Takei, M. (1999). Z-350, A Novel Compound with alpha 1-Adrenoceptor Antagonistic and Steroid 5alpha -Reductase Inhibitory Actions: Pharmacological Properties In Vivo. J. Pharmacol. Exp. Ther. 290: 1013-1018 [Abstract] [Full Text]  
• Litwin, M. S. (1999). Urology. JAMA 281: 495-496 [Full Text]  
• Wilt, T. J., Ishani, A., Stark, G., MacDonald, R., Lau, J., Mulrow, C. (1998). Saw Palmetto Extracts for Treatment of Benign Prostatic Hyperplasia: A Systematic Review. JAMA 280: 1604-1609 [Abstract] [Full Text]  
• (1998). Does Finasteride Prevent BPH Surgery and Urinary Retention?. JWatch General 1998: 3-3 [Full Text]