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Previous Volume 338:613-615 February 26, 1998 Number 9 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text Purchase this article Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited Related Article by Silva, M. Related Article by Moliterno, A. R. Related Article by Ransohoff, R. M. PubMed Citation

In the course of a day, the bone marrow of an adult produces over 10¹¹ cells — mainly erythrocytes, but also granulocytes, monocytes, lymphocytes, and platelets. This enormous output originates from progenitors with the potential to become any kind of blood cell. To begin its passage to a particular lineage, the multipotent precursor must enter a forked pathway and take the branch that leads to committed stem cells. These bipotent or unipotent cells will develop into lineage-specific colony-forming units, the immediate precursors of mature blood cells. It is unclear how a particular multipotent progenitor becomes a red cell rather than . . . [Full Text of this Article]

References

This article has been cited by other articles:

• Moliterno, A. R., Spivak, J. L. (1999). Posttranslational Processing of the Thrombopoietin Receptor Is Impaired in Polycythemia Vera. Blood 94: 2555-2561 [Abstract] [Full Text]