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Correspondence
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Volume 338:623 February 26, 1998 Number 9
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Anaphylaxis from the Carboxymethylcellulose Component of Barium Sulfate Suspension

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To the Editor: In their report of an anaphylactic reaction caused by the carboxymethylcellulose component of barium sulfate suspension (Oct. 30 issue),1 Muroi and colleagues refer to another case report 2 of an anaphylactic reaction during barium administration. They appear to cite the reference as an example of exposure to latex, which has been implicated among the causes of allergic reactions to barium contrast medium. The case report 2 demonstrated that carrageenan, a sulfated polysaccharide that is also used as a suspending agent in barium preparations, was the cause of the anaphylactic reaction, on the basis of positive skin-puncture testing and the . . . [Full Text of this Article]

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