Background Cardiovascular disease is common in patients on long-termdialysis, and it accounts for 44 percent of overall mortalityin this group. We undertook a study to assess long-term survivalafter acute myocardial infarction among patients in the UnitedStates who were receiving long-term dialysis.
Methods Patients on dialysis who were hospitalized during theperiod from 1977 to 1995 for a first myocardial infarction afterthe initiation of renal-replacement therapy were retrospectivelyidentified from the U.S. Renal Data System data base. Overallmortality and mortality from cardiac causes (including all in-hospitaldeaths) were estimated by the life-table method. The effectof independent predictors on survival was examined in a Coxregression model with adjustment for existing illnesses.
Results The overall mortality (±SE) after acute myocardialinfarction among 34,189 patients on long-term dialysis was 59.3±0.3percent at one year, 73.0±0.3 percent at two years, and89.9±0.2 percent at five years. The mortality from cardiaccauses was 40.8±0.3 percent at one year, 51.8±0.3percent at two years, and 70.2±0.4 percent at five years.Patients who were older or had diabetes had higher mortalitythan patients without these characteristics. Adverse outcomesoccurred even in patients who had acute myocardial infarctionin 1990 through 1995. Also, the mortality rate after myocardialinfarction was considerably higher for patients on long-termdialysis than for renal-transplant recipients.
Conclusions Patients on dialysis who have acute myocardial infarctionhave high mortality from cardiac causes and poor long-term survival.
Source Information
From the Divisions of Cardiology (C.A.H.) and Nephrology (J.Z.M., A.J.C.), Department of Internal Medicine, Hennepin County Medical Center and University of Minnesota, Minneapolis.
Address reprint requests to Dr. Herzog at the Hennepin County Medical Center, 701 Park Ave., Minneapolis, MN 55415.
Hayashi, T., Obi, Y., Kimura, T., Iio, K.-i., Sumitsuji, S., Takeda, Y., Nagai, Y., Imai, E.
(2008). Cardiac troponin T predicts occult coronary artery stenosis in patients with chronic kidney disease at the start of renal replacement therapy. Nephrol Dial Transplant
23: 2936-2942
[Abstract][Full Text]
Rabkin, R., Awwad, I., Chen, Y., Ashley, E. A., Sun, D., Sood, S., Clusin, W., Heidenreich, P., Piecha, G., Gross, M.-L.
(2008). Low-Dose Growth Hormone is Cardioprotective in Uremia. J. Am. Soc. Nephrol.
19: 1774-1783
[Abstract][Full Text]
Tsagalis, G., Akrivos, T., Alevizaki, M., Manios, E., Stamatellopoulos, K., Laggouranis, A., Vemmos, K. N.
(2008). Renal dysfunction in acute stroke: an independent predictor of long-term all combined vascular events and overall mortality. Nephrol Dial Transplant
0: gfn471v1-gfn471
[Abstract][Full Text]
Trivedi, H., Xiang, Q., Klein, J. P.
(2008). Risk factors for non-fatal myocardial infarction and cardiac death in incident dialysis patients. Nephrol Dial Transplant
0: gfn426v1-gfn426
[Abstract][Full Text]
Johnston, N., Dargie, H., Jardine, A.
(2008). Diagnosis and treatment of coronary artery disease in patients with chronic kidney disease. Heart
94: 1080-1088
[Full Text]
Goldenberg, I., Vyas, A. K., Hall, W. J., Moss, A. J., Wang, H., He, H., Zareba, W., McNitt, S., Andrews, M. L., for the MADIT-II Investigators,
(2008). Risk Stratification for Primary Implantation of a Cardioverter-Defibrillator in Patients With Ischemic Left Ventricular Dysfunction. J Am Coll Cardiol
51: 288-296
[Abstract][Full Text]
Herzog, C. A.
(2008). Kidney disease in cardiology. Nephrol Dial Transplant
23: 42-46
[Abstract][Full Text]
Banerjee, D., Ma, J. Z., Collins, A. J., Herzog, C. A.
(2007). Long-Term Survival of Incident Hemodialysis Patients Who Are Hospitalized for Congestive Heart Failure, Pulmonary Edema, or Fluid Overload. CJASN
2: 1186-1190
[Abstract][Full Text]
Tanaka, Y., Joki, N., Hase, H.
(2007). History of acute coronary events during the predialysis phase of chronic kidney disease is a strong risk factor for major adverse cardiac events in patients initiating haemodialysis. Nephrol Dial Transplant
22: 2917-2923
[Abstract][Full Text]
Herzog, C. A., Littrell, K., Arko, C., Frederick, P. D., Blaney, M.
(2007). Clinical Characteristics of Dialysis Patients With Acute Myocardial Infarction in the United States: A Collaborative Project of the United States Renal Data System and the National Registry of Myocardial Infarction. Circulation
116: 1465-1472
[Abstract][Full Text]
Taneja, S., Mandayam, S., Kayani, Z. Z., Kuo, Y.-F., Shahinian, V. B.
(2007). Comparison of Stage at Diagnosis of Cancer in Patients Who Are on Dialysis versus the General Population. CJASN
2: 1008-1013
[Abstract][Full Text]
Schiffrin, E. L., Lipman, M. L., Mann, J. F.E.
(2007). Chronic Kidney Disease: Effects on the Cardiovascular System. Circulation
116: 85-97
[Abstract][Full Text]
John, R., Lietz, K., Huddleston, S., Matas, A., Liao, K., Shumway, S., Joyce, L., Bolman, R. M.
(2007). Perioperative outcomes of cardiac surgery in kidney and kidney pancreas transplant recipients. J. Thorac. Cardiovasc. Surg.
133: 1212-1219
[Abstract][Full Text]
Sharma, R., Chemla, E., Tome, M., Mehta, R. L, Gregson, H., Brecker, S. J D, Chang, R., Pellerin, D.
(2007). Echocardiography-based score to predict outcome after renal transplantation. Heart
93: 464-469
[Abstract][Full Text]
Edwards, N.C., Steeds, R.P., Ferro, C.J., Townend, J.N.
(2006). The treatment of coronary artery disease in patients with chronic kidney disease. QJM
99: 723-736
[Abstract][Full Text]
Rakhit, D J, Marwick, T H, Armstrong, K A, Johnson, D W, Leano, R, Isbel, N M
(2006). Effect of aggressive risk factor modification on cardiac events and myocardial ischaemia in patients with chronic kidney disease. Heart
92: 1402-1408
[Abstract][Full Text]
Jose, P., Skali, H., Anavekar, N., Tomson, C., Krumholz, H. M., Rouleau, J. L., Moye, L., Pfeffer, M. A., Solomon, S. D., for the SAVE Investigators,
(2006). Increase in Creatinine and Cardiovascular Risk in Patients with Systolic Dysfunction after Myocardial Infarction. J. Am. Soc. Nephrol.
17: 2886-2891
[Abstract][Full Text]
Yoshida, H., Yokoyama, K., Maruvama, Y., Yamanoto, H., Yoshida, S., Hosoya, T.
(2006). Investigation of coronary artery calcification and stenosis by coronary angiography (CAG) in haemodialysis patients. Nephrol Dial Transplant
21: 1451-1452
[Full Text]
Kutner, N. G., Zhang, R., Huang, Y., Herzog, C. A.
(2006). Cardiac Rehabilitation and Survival of Dialysis Patients after Coronary Bypass. J. Am. Soc. Nephrol.
17: 1175-1180
[Abstract][Full Text]
Dewey, T. M., Herbert, M. A., Prince, S. L., Robbins, C. L., Worley, C. M., Magee, M. J., Mack, M. J.
(2006). Does Coronary Artery Bypass Graft Surgery Improve Survival Among Patients With End-Stage Renal Disease?. Ann. Thorac. Surg.
81: 591-598
[Abstract][Full Text]
Berl, T., Henrich, W.
(2006). Kidney-Heart Interactions: Epidemiology, Pathogenesis, and Treatment. CJASN
1: 8-18
[Full Text]
Khan, N. A., Ma, I., Thompson, C. R., Humphries, K., Salem, D. N., Sarnak, M. J., Levin, A.
(2006). Kidney Function and Mortality among Patients with Left Ventricular Systolic Dysfunction. J. Am. Soc. Nephrol.
17: 244-253
[Abstract][Full Text]
Tonelli, M., Keech, A., Shepherd, J., Sacks, F., Tonkin, A., Packard, C., Pfeffer, M., Simes, J., Isles, C., Furberg, C., West, M., Craven, T., Curhan, G.
(2005). Effect of Pravastatin in People with Diabetes and Chronic Kidney Disease. J. Am. Soc. Nephrol.
16: 3748-3754
[Abstract][Full Text]
Shlipak, M., Stehman-Breen, C.
(2005). Observational Research Databases in Renal Disease. J. Am. Soc. Nephrol.
16: 3477-3484
[Abstract][Full Text]
Lauer, M. S.
(2005). Cardiac Troponins and Renal Failure: The Evolution of a Clinical Test. Circulation
112: 3036-3037
[Full Text]
Khan, N. A., Hemmelgarn, B. R., Tonelli, M., Thompson, C. R., Levin, A.
(2005). Prognostic Value of Troponin T and I Among Asymptomatic Patients With End-Stage Renal Disease: A Meta-Analysis. Circulation
112: 3088-3096
[Abstract][Full Text]
Nolan, C. R.
(2005). Strategies for Improving Long-Term Survival in Patients with ESRD. J. Am. Soc. Nephrol.
16: S120-S127
[Abstract][Full Text]
Holzmann, M. J., Ahnve, S., Hammar, N., Jorgensen, L., Klerdal, K., Pehrsson, K., Ivert, T.
(2005). Creatinine clearance and risk of early mortality in patients undergoing coronary artery bypass grafting. J. Thorac. Cardiovasc. Surg.
130: 746-746
[Abstract][Full Text]
Fragedaki, E., Nebel, M., Schupp, N., Sebekova, K., Volkel, W., Klassen, A., Pischetsrieder, M., Frischmann, M., Niwa, T., Vienken, J., Heidland, A., Stopper, H.
(2005). Genomic damage and circulating AGE levels in patients undergoing daily versus standard haemodialysis. Nephrol Dial Transplant
20: 1936-1943
[Abstract][Full Text]
Massad, M. G., Kpodonu, J., Lee, J., Espat, J., Gandhi, S., Tevar, A., Geha, A. S.
(2005). Outcome of Coronary Artery Bypass Operations in Patients With Renal Insufficiency With and Without Renal Transplantation. Chest
128: 855-862
[Abstract][Full Text]
Vanholder, R., Massy, Z., Argiles, A., Spasovski, G., Verbeke, F., Lameire, N., for the European Uremic Toxin Work Group (EUTox),
(2005). Chronic kidney disease as cause of cardiovascular morbidity and mortality. Nephrol Dial Transplant
20: 1048-1056
[Abstract][Full Text]
de Araujo Goncalves, P., Ferreira, J., Aguiar, C., Seabra-Gomes, R.
(2005). TIMI, PURSUIT, and GRACE risk scores: sustained prognostic value and interaction with revascularization in NSTE-ACS. Eur Heart J
26: 865-872
[Abstract][Full Text]
Parekh, R. S., Zhang, L., Fivush, B. A., Klag, M. J.
(2005). Incidence of Atherosclerosis by Race in the Dialysis Morbidity and Mortality Study: A Sample of the US ESRD Population. J. Am. Soc. Nephrol.
16: 1420-1426
[Abstract][Full Text]
Ohtake, T., Kobayashi, S., Moriya, H., Negishi, K., Okamoto, K., Maesato, K., Saito, S.
(2005). High Prevalence of Occult Coronary Artery Stenosis in Patients with Chronic Kidney Disease at the Initiation of Renal Replacement Therapy: An Angiographic Examination. J. Am. Soc. Nephrol.
16: 1141-1148
[Abstract][Full Text]
van de Wal, R. M.A., van Brussel, B. L., Voors, A. A., Smilde, T. D.J., Kelder, J. C., van Swieten, H. A., van Gilst, W. H., van Veldhuisen, D. J., Plokker, H.W. T.
(2005). Mild preoperative renal dysfunction as a predictor of long-term clinical outcome after coronary bypass surgery. J. Thorac. Cardiovasc. Surg.
129: 330-335
[Abstract][Full Text]
Lentine, K. L., Brennan, D. C., Schnitzler, M. A.
(2005). Incidence and Predictors of Myocardial Infarction after Kidney Transplantation. J. Am. Soc. Nephrol.
16: 496-506
[Abstract][Full Text]
Bongartz, L. G., Cramer, M. J., Doevendans, P. A., Joles, J. A., Braam, B.
(2005). The severe cardiorenal syndrome: 'Guyton revisited'. Eur Heart J
26: 11-17
[Abstract][Full Text]
Tokmakova, M. P., Skali, H., Kenchaiah, S., Braunwald, E., Rouleau, J. L., Packer, M., Chertow, G. M., Moye, L. A., Pfeffer, M. A., Solomon, S. D.
(2004). Chronic Kidney Disease, Cardiovascular Risk, and Response to Angiotensin-Converting Enzyme Inhibition After Myocardial Infarction: The Survival And Ventricular Enlargement (SAVE) Study. Circulation
110: 3667-3673
[Abstract][Full Text]
Herzog, C. A.
(2004). Don't forget the defibrillator in the dialysis unit. Nephrol Dial Transplant
19: 2959-2960
[Full Text]
Marenzi, G., Lauri, G., Assanelli, E., Campodonico, J., De Metrio, M., Marana, I., Grazi, M., Veglia, F., Bartorelli, A. L.
(2004). Contrast-induced nephropathy in patients undergoing primary angioplasty for acute myocardial infarction. J Am Coll Cardiol
44: 1780-1785
[Abstract][Full Text]
Gupta, R., Birnbaum, Y., Uretsky, B. F.
(2004). The renal patient with coronary artery disease: Current concepts and dilemmas. J Am Coll Cardiol
44: 1343-1353
[Abstract][Full Text]
Trachiotis, G. D., Hanumara, D., McKenna, L., Corso, P., Pfister, A.
(2004). Surgical revascularization after acute myocardial infarction in patients with end-stage renal disease. Eur. J. Cardiothorac. Surg.
26: 671-675
[Abstract][Full Text]
Koch, M., Trapp, R., Kulas, W., Grabensee, B.
(2004). Critical limb ischaemia as a main cause of death in patients with end-stage renal disease: a single-centre study. Nephrol Dial Transplant
19: 2547-2552
[Abstract][Full Text]
Anavekar, N. S., McMurray, J. J.V., Velazquez, E. J., Solomon, S. D., Kober, L., Rouleau, J.-L., White, H. D., Nordlander, R., Maggioni, A., Dickstein, K., Zelenkofske, S., Leimberger, J. D., Califf, R. M., Pfeffer, M. A.
(2004). Relation between Renal Dysfunction and Cardiovascular Outcomes after Myocardial Infarction. NEJM
351: 1285-1295
[Abstract][Full Text]
Tonelli, M., Isles, C., Curhan, G. C., Tonkin, A., Pfeffer, M. A., Shepherd, J., Sacks, F. M., Furberg, C., Cobbe, S. M., Simes, J., Craven, T., West, M.
(2004). Effect of Pravastatin on Cardiovascular Events in People With Chronic Kidney Disease. Circulation
110: 1557-1563
[Abstract][Full Text]
Mueller, C, Neumann, F-J, Perruchoud, A P, Buettner, H J
(2004). Renal function and long term mortality after unstable angina/non-ST segment elevation myocardial infarction treated very early and predominantly with percutaneous coronary intervention. Heart
90: 902-907
[Abstract][Full Text]
Herzog, C. A., Ma, J. Z., Collins, A. J.
(2004). Long-Term Outcome of Renal Transplant Recipients in the United States After Coronary Revascularization Procedures. Circulation
109: 2866-2871
[Abstract][Full Text]
Dikow, R., Kihm, L. P., Zeier, M., Kapitza, J., Tornig, J., Amann, K., Tiefenbacher, C., Ritz, E.
(2004). Increased Infarct Size in Uremic Rats: Reduced Ischemia Tolerance?. J. Am. Soc. Nephrol.
15: 1530-1536
[Abstract][Full Text]
Okubo, K., Ikewaki, K., Sakai, S., Tada, N., Kawaguchi, Y., Mochizuki, S.
(2004). Abnormal HDL Apolipoprotein A-I and A-II Kinetics in Hemodialysis Patients: A Stable Isotope Study. J. Am. Soc. Nephrol.
15: 1008-1015
[Abstract][Full Text]
Beddhu, S., Pappas, L. M., Ramkumar, N., Samore, M. H.
(2004). Malnutrition and Atherosclerosis in Dialysis Patients. J. Am. Soc. Nephrol.
15: 733-742
[Abstract][Full Text]
Mitchell, G. F.
(2004). Increased Aortic Stiffness: An Unfavorable Cardiorenal Connection. Hypertension
43: 151-153
[Full Text]
Trovati, M., Cavalot, F.
(2004). Optimization of Hypolipidemic and Antiplatelet Treatment in the Diabetic Patient with Renal Disease. J. Am. Soc. Nephrol.
15: S12-20
[Abstract][Full Text]
Locatelli, F., Pozzoni, P., Del Vecchio, L.
(2004). Renal Replacement Therapy in Patients with Diabetes and End-Stage Renal Disease. J. Am. Soc. Nephrol.
15: S25-29
[Abstract][Full Text]
Sadeghi, H. M., Stone, G. W., Grines, C. L., Mehran, R., Dixon, S. R., Lansky, A. J., Fahy, M., Cox, D. A., Garcia, E., Tcheng, J. E., Griffin, J. J., Stuckey, T. D., Turco, M., Carroll, J. D.
(2003). Impact of Renal Insufficiency in Patients Undergoing Primary Angioplasty for Acute Myocardial Infarction. Circulation
108: 2769-2775
[Abstract][Full Text]
French, W. J., Wright, R. S.
(2003). Renal insufficiency and worsened prognosis with STEMI: A call for action. J Am Coll Cardiol
42: 1544-1546
[Full Text]
Sarnak, M. J., Levey, A. S., Schoolwerth, A. C., Coresh, J., Culleton, B., Hamm, L. L., McCullough, P. A., Kasiske, B. L., Kelepouris, E., Klag, M. J., Parfrey, P., Pfeffer, M., Raij, L., Spinosa, D. J., Wilson, P. W.
(2003). Kidney Disease as a Risk Factor for Development of Cardiovascular Disease: A Statement From the American Heart Association Councils on Kidney in Cardiovascular Disease, High Blood Pressure Research, Clinical Cardiology, and Epidemiology and Prevention. Hypertension
42: 1050-1065
[Full Text]
Sarnak, M. J., Levey, A. S., Schoolwerth, A. C., Coresh, J., Culleton, B., Hamm, L. L., McCullough, P. A., Kasiske, B. L., Kelepouris, E., Klag, M. J., Parfrey, P., Pfeffer, M., Raij, L., Spinosa, D. J., Wilson, P. W.
(2003). Kidney Disease as a Risk Factor for Development of Cardiovascular Disease: A Statement From the American Heart Association Councils on Kidney in Cardiovascular Disease, High Blood Pressure Research, Clinical Cardiology, and Epidemiology and Prevention. Circulation
108: 2154-2169
[Full Text]
Dikow, R., Ritz, E.
(2003). Cardiovascular complications in the diabetic patient with renal disease: an update in 2003. Nephrol Dial Transplant
18: 1993-1998
[Full Text]
Ashman, N., Macey, M. G., Fan, S. L., Azam, U., Yaqoob, M. M.
(2003). Increased platelet-monocyte aggregates and cardiovascular disease in end-stage renal failure patients. Nephrol Dial Transplant
18: 2088-2096
[Abstract][Full Text]
Cooper, W. A., Brinkman, W., Petersen, R. J., Guyton, R. A.
(2003). Impact of renal disease in cardiovascular surgery: emphasis on the African-American patient. Ann. Thorac. Surg.
76: S1370-1376
[Abstract][Full Text]
Herzog, C. A.
(2003). How to Manage the Renal Patient with Coronary Heart Disease: The Agony and the Ecstasy of Opinion-Based Medicine. J. Am. Soc. Nephrol.
14: 2556-2572
[Full Text]
Wong, D., Thompson, G., Buth, K., Sullivan, J., Ali, I.
(2003). Angiographic coronary diffuseness and outcomes in dialysis patients undergoing coronary artery bypass grafting surgery. Eur. J. Cardiothorac. Surg.
24: 388-392
[Abstract][Full Text]
Levin, A.
(2003). The advantage of a uniform terminology and staging system for chronic kidney disease (CKD). Nephrol Dial Transplant
18: 1446-1451
[Full Text]
Levin, A.
(2003). The advantage of a uniform terminology and staging system for chronic kidney disease (CKD). Nephrol Dial Transplant
18: 1446-1451
[Full Text]
Berger, A. K., Duval, S., Krumholz, H. M.
(2003). Aspirin, beta-blocker, and angiotensin-converting enzyme inhibitor therapy in patients with end-stage renal disease and an acute myocardial infarction. J Am Coll Cardiol
42: 201-208
[Abstract][Full Text]
Reddan, D. N., Klassen, P. S., Szczech, L. A., Coladonato, J. A., O'Shea, S., Owen, W. F. Jr, Lowrie, E. G.
(2003). White blood cells as a novel mortality predictor in haemodialysis patients. Nephrol Dial Transplant
18: 1167-1173
[Abstract][Full Text]
Amann, K., Ritz, C., Adamczak, M., Ritz, E.
(2003). Why is coronary heart disease of uraemic patients so frequent and so devastating?. Nephrol Dial Transplant
18: 631-640
[Abstract][Full Text]
Freeman, R. V., Mehta, R. H., Al Badr, W., Cooper, J. V., Kline-Rogers, E., Eagle, K. A.
(2003). Influence of concurrent renal dysfunction on outcomes of patients with acute coronary syndromes and implications of the use of glycoprotein IIb/IIIa inhibitors. J Am Coll Cardiol
41: 718-724
[Abstract][Full Text]
Tepel, M., van der Giet, M., Statz, M., Jankowski, J., Zidek, W.
(2003). The Antioxidant Acetylcysteine Reduces Cardiovascular Events in Patients With End-Stage Renal Failure: A Randomized, Controlled Trial. Circulation
107: 992-995
[Abstract][Full Text]
Rabbat, C. G., Treleaven, D. J., Russell, J. D., Ludwin, D., Cook, D. J.
(2003). Prognostic Value of Myocardial Perfusion Studies in Patients with End-Stage Renal Disease Assessed for Kidney or Kidney-Pancreas Transplantation: A Meta-Analysis. J. Am. Soc. Nephrol.
14: 431-439
[Abstract][Full Text]
McCullough, P. A., Nowak, R. M., Foreback, C., Tokarski, G., Tomlanovich, M. C., Khoury, N., Weaver, W. D., Sandberg, K. R., McCord, J.
(2002). Emergency Evaluation of Chest Pain in Patients With Advanced Kidney Disease. Arch Intern Med
162: 2464-2468
[Abstract][Full Text]
Herzog, C. A., Ma, J. Z., Collins, A. J.
(2002). Comparative Survival of Dialysis Patients in the United States After Coronary Angioplasty, Coronary Artery Stenting, and Coronary Artery Bypass Surgery and Impact of Diabetes. Circulation
106: 2207-2211
[Abstract][Full Text]
Chow, K. M., Szeto, C. C., Wong, T. Y.-h., Leung, F. K.-t., Cheuk, A., Li, P. K.-t.
(2002). Diabetic Muscle Infarction: Myocardial infarct equivalent. Diabetes Care
25: 1895-1895
[Full Text]
Shlipak, M. G., Heidenreich, P. A., Noguchi, H., Chertow, G. M., Browner, W. S., McClellan, M. B.
(2002). Association of Renal Insufficiency with Treatment and Outcomes after Myocardial Infarction in Elderly Patients. ANN INTERN MED
137: 555-562
[Abstract][Full Text]
Wright, R. S., Reeder, G. S., Herzog, C. A., Albright, R. C., Williams, B. A., Dvorak, D. L., Miller, W. L., Murphy, J. G., Kopecky, S. L., Jaffe, A. S.
(2002). Acute Myocardial Infarction and Renal Dysfunction: A High-Risk Combination. ANN INTERN MED
137: 563-570
[Abstract][Full Text]
Townsend, R. R.
(2002). Cardiac Mortality in Chronic Kidney Disease: A Clearer Perspective. ANN INTERN MED
137: 615-616
[Full Text]
McCullough, P. A, Sandberg, K. R, Yee, J., Hudson, M. P
(2002). Mortality benefit of angiotensin-converting enzyme inhibitors after cardiac events in patients with end-stage renal disease. Journal of Renin-Angiotensin-Aldosterone System
3: 188-191
[Abstract]
Al Suwaidi, J., Reddan, D. N., Williams, K., Pieper, K. S., Harrington, R. A., Califf, R. M., Granger, C. B., Ohman, E. M., Holmes, D. R. Jr, for the GUSTO-IIb, GUSTO-III, PURSUIT, and PARAGON,
(2002). Prognostic Implications of Abnormalities in Renal Function in Patients With Acute Coronary Syndromes. Circulation
106: 974-980
[Abstract][Full Text]
Dacey, L. J., Liu, J. Y., Braxton, J. H., Weintraub, R. M., DeSimone, J., Charlesworth, D. C., Lahey, S. J., Ross, C. S., Hernandez, F. Jr, Leavitt, B. J., O'Connor, G. T.
(2002). Long-term survival of dialysis patients after coronary bypass grafting. Ann. Thorac. Surg.
74: 458-463
[Abstract][Full Text]
Longenecker, J. C., Coresh, J., Powe, N. R., Levey, A. S., Fink, N. E., Martin, A., Klag, M. J.
(2002). Traditional Cardiovascular Disease Risk Factors in Dialysis Patients Compared with the General Population: The CHOICE Study. J. Am. Soc. Nephrol.
13: 1918-1927
[Abstract][Full Text]
Januzzi, J. L. Jr, Snapinn, S. M., DiBattiste, P. M., Jang, I.-K., Theroux, P.
(2002). Benefits and Safety of Tirofiban Among Acute Coronary Syndrome Patients With Mild to Moderate Renal Insufficiency: Results From the Platelet Receptor Inhibition in Ischemic Syndrome Management in Patients Limited by Unstable Signs and Symptoms (PRISM-PLUS) Trial. Circulation
105: 2361-2366
[Abstract][Full Text]
Szczech, L.A., Best, P.J., Crowley, E., Brooks, M.M., Berger, P.B., Bittner, V., Gersh, B.J., Jones, R., Califf, R.M., Ting, H.H., Whitlow, P.J., Detre, K.M., Holmes, D., for the Bypass Angioplasty Revascularization Inves,
(2002). Outcomes of Patients With Chronic Renal Insufficiency in the Bypass Angioplasty Revascularization Investigation. Circulation
105: 2253-2258
[Abstract][Full Text]
Herzog, C. A.
(2002). Dismal long-term survival of dialysis patients after acute myocardial infarction: can we alter the outcome?. Nephrol Dial Transplant
17: 7-10
[Full Text]
Jardine, A. G, McLaughlin, K.
(2001). GENERAL CARDIOLOGY: Cardiovascular complications of renal disease. Heart
86: 459-466
[Full Text]
Shlipak, M. G., Simon, J. A., Grady, D., Lin, F., Wenger, N. K., Furberg, C. D., for the Heart and Estrogen/progestin Replacement S,
(2001). Renal insufficiency and cardiovascular events in postmenopausal women with coronary heart disease. J Am Coll Cardiol
38: 705-711
[Abstract][Full Text]
Gradaus, F., Ivens, K., Peters, A. J., Heering, P., Schoebel, F.-C., Grabensee, B., Strauer, B.-E.
(2001). Angiographic progression of coronary artery disease in patients with end-stage renal disease. Nephrol Dial Transplant
16: 1198-1202
[Abstract][Full Text]
Le Feuvre, C, Dambrin, G, Helft, G, Beygui, F, Touam, M, Grünfeld, J P, Vacheron, A, Metzger, J P
(2001). Clinical outcome following coronary angioplasty in dialysis patients: a case-control study in the era of coronary stenting. Heart
85: 556-560
[Abstract][Full Text]
Ooi, D. S., Zimmerman, D., Graham, J., Wells, G. A.
(2001). Cardiac Troponin T Predicts Long-Term Outcomes in Hemodialysis Patients. Clin. Chem.
47: 412-417
[Abstract][Full Text]
Rump, L. C., Amann, K., Orth, S., Ritz, E.
(2000). Sympathetic overactivity in renal disease: a window to understand progression and cardiovascular complications of uraemia?. Nephrol Dial Transplant
15: 1735-1738
[Full Text]
Iseki, K., Fukiyama, K.
(2000). Clinical demographics and long-term prognosis after stroke in patients on chronic haemodialysis. Nephrol Dial Transplant
15: 1808-1813
[Abstract][Full Text]
Amann, K., Ritz, E.
(2000). Microvascular disease--the Cinderella of uraemic heart disease. Nephrol Dial Transplant
15: 1493-1503
[Abstract][Full Text]
McCullough, P. A., Soman, S. S., Shah, S. S., Smith, S. T., Marks, K. R., Yee, J., Borzak, S.
(2000). Risks associated with renal dysfunction in patients in the coronary care unit. J Am Coll Cardiol
36: 679-684
[Abstract][Full Text]
Franga, D. L., Kratz, J. M., Crumbley, A. J., Zellner, J. L., Stroud, M. R., Crawford, F. A.
(2000). Early and long-term results of coronary artery bypass grafting in dialysis patients. Ann. Thorac. Surg.
70: 813-818
[Abstract][Full Text]
PASSAUER, J., BÜSSEMAKER, E., RANGE, U., PLUG, M., GROSS, P.
(2000). Evidence In Vivo Showing Increase of Baseline Nitric Oxide Generation and Impairment of Endothelium-Dependent Vasodilation in Normotensive Patients on Chronic Hemodialysis. J. Am. Soc. Nephrol.
11: 1726-1734
[Abstract][Full Text]
LE FEUVRE, C
(2000). Angioplasty and stenting in patients with renal disease. Heart
83: 7-8
[Full Text]
Previous
