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Editorial
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Volume 339:841-843 September 17, 1998 Number 12
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Chronic Renal Failure — A Vasculopathic State

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 by Herzog, C. A.
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Chronic renal insufficiency (defined by a serum creatinine concentration of 1.5 to 3.0 mg per deciliter [133 to 265 µmol per liter]), chronic renal failure (serum creatinine concentration, >3.0 mg per deciliter), and end-stage renal disease should be regarded as parts of a continuum. Of the 300,000 patients who are currently receiving renal-replacement therapy in the United States,1 220,000 receive dialysis therapy and the remainder depend on a successful kidney graft. The current annual increase in the number of patients receiving renal-replacement therapy is 6 to 7 percent; by extrapolation,2 at least 600,000 patients will be receiving such therapy by . . . [Full Text of this Article]

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