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Volume 339:990-995 October 1, 1998 Number 14
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Sentinel-Lymph-Node Biopsy for Breast Cancer — Not Yet the Standard of Care

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A sentinel lymph node is the first lymph node to receive lymphatic drainage from a tumor. It can be detected by injection of a blue dye or radioactive colloid around the primary tumor, which travels to and identifies the first draining (sentinel) node. Biopsy of a sentinel lymph node can reveal whether there are lymphatic metastases, thereby obviating the need for extensive dissection of the regional lymph-node basin. Sentinel-lymph-node biopsy has become a standard technique for determining the nodal stage of disease in patients with melanoma. Initial studies of this method in patients with breast cancer suggest that sentinel-lymph-node biopsy . . . [Full Text of this Article]

Assessing the Accuracy of Sentinel-Lymph-Node Biopsy

Melanoma

Breast Cancer

The Importance of Axillary Nodal Staging

The Therapeutic Value of Axillary Lymph-Node Dissection

Sentinel-Lymph-Node Biopsy for Nodal Staging

Technical Issues

Summary

Address reprint requests to Dr. McMasters at the University of Louisville–Brown Cancer Center, 529 S. Jackson St., Louisville, KY 40202.

References


Related Letters:

Sentinel-Lymph-Node Biopsy
Schillaci O., Scopinaro F., Abramson L. R., Retsas S., Krag D. N., Moffat F. L., Ashikaga T., McMasters K. M., Edwards M. J., Ross M. I.
Extract | Full Text  
N Engl J Med 1999; 340:317-319, Jan 28, 1999. Correspondence

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