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Previous Volume 339:1076-1078 October 8, 1998 Number 15 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Immunochemists have been making precise measurements of antibodies and antigens for many years, whereas cellular immunologists have had to rely on indirect and often clumsy methods for counting T cells with specificity for a particular antigen. Recently, several laboratories have shown how to enumerate antigen-specific T cells directly and have applied the method to clinical problems. With this medically important advance, physicians can obtain counts of circulating cytotoxic T cells with immunologic specificity for a given pathogenic virus. The method requires only existing equipment (a fluorescence-activated cell sorter) and reagents that will probably soon be commercially available. Knowledge of the . . . [Full Text of this Article]

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This article has been cited by other articles:

• Whelan, J. A., Dunbar, P. R., Price, D. A., Purbhoo, M. A., Lechner, F., Ogg, G. S., Griffiths, G., Phillips, R. E., Cerundolo, V., Sewell, A. K. (1999). Specificity of CTL Interactions with Peptide-MHC Class I Tetrameric Complexes Is Temperature Dependent. J. Immunol. 163: 4342-4348 [Abstract] [Full Text]