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Previous Volume 339:1083-1084 October 8, 1998 Number 15 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: We commend Berenson et al. (June 4 issue)¹ for identifying risk factors associated with the development of atherosclerosis in young people. However, we are concerned that the failure to include cocaine as a risk factor for atherosclerosis may have resulted in an overestimation of the contribution of other risk factors.

The vast majority of persons studied were victims of homicide and accidents. Several investigations have demonstrated a link between victims of trauma and cocaine use. Cocaine metabolites have been identified in up to 31 percent of homicide victims and 25 percent of persons arrested for reckless driving.^2,3

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References

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• Charakida, M., Donald, A. E., Terese, M., Leary, S., Halcox, J. P., Ness, A., Smith, G. D., Golding, J., Friberg, P., Klein, N. J., Deanfield, J. E., for the ALSPAC (Avon Longitudinal Study of Parents, (2005). Endothelial Dysfunction in Childhood Infection. Circulation 111: 1660-1665 [Abstract] [Full Text]  
• Cole, J. H., Miller, J. I. III, Sperling, L. S., Weintraub, W. S. (2003). Long-term follow-up of coronary artery disease presenting in young adults. J Am Coll Cardiol 41: 521-528 [Abstract] [Full Text]  
• Klein, L. W., Nathan, S. (2003). Coronary artery disease in young adults. J Am Coll Cardiol 41: 529-531 [Full Text]