Benefit of a Favorable Cardiovascular Risk-Factor Profile in Middle Age with Respect to Medicare Costs
Martha L. Daviglus, M.D., Ph.D., Kiang Liu, Ph.D., Philip Greenland, M.D., Alan R. Dyer, Ph.D., Daniel B. Garside, Larry Manheim, Ph.D., Lynn P. Lowe, Ph.D., Miriam Rodin, M.D., Ph.D., James Lubitz, M.P.H., and Jeremiah Stamler, M.D.
Background People without major risk factors for cardiovasculardisease in middle age live longer than those with unfavorablerisk-factor profiles. It is not known whether such low-riskstatus also results in lower expenditures for medical care atolder ages. We used data from the Chicago Heart AssociationDetection Project in Industry to assess the relation of a lowrisk of cardiovascular disease in middle age to Medicare expenditureslater in life.
Methods We studied 7039 men and 6757 women who were 40 to 64years of age when surveyed between 1967 and 1973 and who survivedto have at least two years of Medicare coverage in 1984 through1994. Men and women classified as being at low risk for cardiovasculardisease were those who had the following characteristics atthe time they were initially surveyed: serum cholesterol level,<200 mg per deciliter (5.2 mmol per liter); blood pressure,120/80 mm Hg; no current smoking; an absence of electrocardiographicabnormalities; no history of diabetes; and no history of myocardialinfarction. We compared Medicare costs for the 279 men (4.0percent) and 298 women (4.4 percent) who had this low-risk profilewith those for the rest of the study group, who were not atlow risk. Health Care Financing Administration charges for servicesto Medicare beneficiaries were used to estimate average annualhealth care costs (total costs, those for cardiovascular diseases,and those for cancer).
Results Average annual health care charges were much lower forpersons at low risk the total charges for the men atlow risk were less than two thirds of the charges for the mennot at low risk ($1,615 less); for the women at low risk, thecharges were less than one half of those for the women not atlow risk ($1,885 less). Charges related to cardiovascular diseasewere lower for the low-risk groups of men and women than forthose not at low risk (by $979 and $556, respectively), andcharges related to cancer were also lower (by $134 and $189).
Conclusions People with favorable cardiovascular risk profilesin middle age had lower average annual Medicare charges in olderage. Having optimal status with respect to major cardiovascularrisk factors may result not only in greater longevity but alsoin lower health care costs.
Source Information
From the Department of Preventive Medicine (M.L.D., K.L., P.G., A.R.D., D.B.G., L.P.L., J.S.) and the Department of Medicine, Division of Geriatrics (M.L.D., M.R.), Northwestern University Medical School, Chicago; the Institute for Health Services Research and Policy Studies, Northwestern University, Evanston, Ill. (L.M.); and the Office of Research and Demonstrations, Health Care Financing Administration, Baltimore (J.L.).
Address reprint requests to Dr. Daviglus at the Department of Preventive Medicine, Northwestern University Medical School, 680 N. Lake Shore Dr., Suite 1102, Chicago, IL 60611.
Redberg, R. F., Benjamin, E. J., Bittner, V., Braun, L. T., Goff, D. C. Jr, Havas, S., Labarthe, D. R., Limacher, M. C., Lloyd-Jones, D. M., Mora, S., Pearson, T. A., Radford, M. J., Smetana, G. W., Spertus, J. A., Swegler, E. W.
(2009). ACCF/AHA 2009 performance measures for primary prevention of cardiovascular disease in adults: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Performance Measures (Writing Committee to Develop Performance Measures for Primary Prevention of Cardiovascular Disease) developed in collaboration with the American Academy of Family Physicians; American Association of Cardiovascular and Pulmonary Rehabilitation; and Preventive Cardiovascular Nurses Association Endorsed by the American College of Preventive Medicine, American College of Sports Medicine, and Society for Women's Health Research.. J Am Coll Cardiol
54: 1364-1405
[Full Text]
Ford, E. S., Li, C., Zhao, G., Pearson, W. S., Capewell, S.
(2009). Trends in the Prevalence of Low Risk Factor Burden for Cardiovascular Disease Among United States Adults. Circulation
120: 1181-1188
[Abstract][Full Text]
WRITING COMMITTEE MEMBERS, , Redberg, R. F., Benjamin, E. J., Bittner, V., Braun, L. T., Goff, D. C. Jr, Havas, S., Labarthe, D. R., Limacher, M. C., Lloyd-Jones, D. M., Mora, S., Pearson, T. A., Radford, M. J., Smetana, G. W., Spertus, J. A., Swegler, E. W.
(2009). ACCF/AHA 2009 Performance Measures for Primary Prevention of Cardiovascular Disease in Adults: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Performance Measures (Writing Committee to Develop Performance Measures for Primary Prevention of Cardiovascular Disease): Developed in Collaboration With the American Academy of Family Physicians; American Association of Cardiovascular and Pulmonary Rehabilitation; and Preventive Cardiovascular Nurses Association: Endorsed by the American College of Preventive Medicine, American College of Sports Medicine, and Society for Women's Health Research. Circulation
120: 1296-1336
[Full Text]
Goff, D. C. Jr, Greenland, P.
(2009). The Change We Need in Health Care. Arch Intern Med
169: 737-739
[Full Text]
WRITING GROUP MEMBERS, , Lloyd-Jones, D., Adams, R., Carnethon, M., De Simone, G., Ferguson, T. B., Flegal, K., Ford, E., Furie, K., Go, A., Greenlund, K., Haase, N., Hailpern, S., Ho, M., Howard, V., Kissela, B., Kittner, S., Lackland, D., Lisabeth, L., Marelli, A., McDermott, M., Meigs, J., Mozaffarian, D., Nichol, G., O'Donnell, C., Roger, V., Rosamond, W., Sacco, R., Sorlie, P., Stafford, R., Steinberger, J., Thom, T., Wasserthiel-Smoller, S., Wong, N., Wylie-Rosett, J., Hong, Y., for the American Heart Association Statistics Comm,
(2009). Heart Disease and Stroke Statistics--2009 Update: A Report From the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation
119: e21-e181
[Full Text]
Kottke, T. E., Solberg, L. I., Nelson, A. F., Belcher, D. W., Caplan, W., Green, L. W., Lydick, E., Magid, D. J., Rolnick, S. J., Woolf, S. H.
(2008). Optimizing Practice Through Research: A New Perspective to Solve an Old Problem. Ann Fam Med
6: 459-462
[Abstract][Full Text]
Writing Group Members, , Rosamond, W., Flegal, K., Furie, K., Go, A., Greenlund, K., Haase, N., Hailpern, S. M., Ho, M., Howard, V., Kissela, B., Kittner, S., Lloyd-Jones, D., McDermott, M., Meigs, J., Moy, C., Nichol, G., O'Donnell, C., Roger, V., Sorlie, P., Steinberger, J., Thom, T., Wilson, M., Hong, Y., for the American Heart Association Statistics Comm,
(2008). Heart Disease and Stroke Statistics--2008 Update: A Report From the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation
117: e25-e146
[Full Text]
Lloyd-Jones, D. M., Liu, K., Colangelo, L. A., Yan, L. L., Klein, L., Loria, C. M., Lewis, C. E., Savage, P.
(2007). Consistently Stable or Decreased Body Mass Index in Young Adulthood and Longitudinal Changes in Metabolic Syndrome Components: The Coronary Artery Risk Development in Young Adults Study. Circulation
115: 1004-1011
[Abstract][Full Text]
Rosamond, W., Flegal, K., Friday, G., Furie, K., Go, A., Greenlund, K., Haase, N., Ho, M., Howard, V., Kissela, B., Kittner, S., Lloyd-Jones, D., McDermott, M., Meigs, J., Moy, C., Nichol, G., O'Donnell, C. J., Roger, V., Rumsfeld, J., Sorlie, P., Steinberger, J., Thom, T., Wasserthiel-Smoller, S., Hong, Y., for the American Heart Association Statistics Comm,
(2007). Heart Disease and Stroke Statistics--2007 Update: A Report From the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation
115: e69-e171
[Full Text]
Shaw, L. J., Merz, C. N. B., Pepine, C. J., Reis, S. E., Bittner, V., Kip, K. E., Kelsey, S. F., Olson, M., Johnson, B. D., Mankad, S., Sharaf, B. L., Rogers, W. J., Pohost, G. M., Sopko, G., for the Women's Ischemia Syndrome Evaluation (WISE,
(2006). The Economic Burden of Angina in Women With Suspected Ischemic Heart Disease: Results From the National Institutes of Health-National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation. Circulation
114: 894-904
[Abstract][Full Text]
Chang, H.-Y., Hu, Y.-W., Yue, C.-S. J., Wen, Y.-W., Yeh, W.-T., Hsu, L.-S., Tsai, S.-Y., Pan, W.-H.
(2006). Effect of potassium-enriched salt on cardiovascular mortality and medical expenses of elderly men. Am. J. Clin. Nutr.
83: 1289-1296
[Abstract][Full Text]
Yan, L. L., Daviglus, M. L., Liu, K., Stamler, J., Wang, R., Pirzada, A., Garside, D. B., Dyer, A. R., Van Horn, L., Liao, Y., Fries, J. F., Greenland, P.
(2006). Midlife Body Mass Index and Hospitalization and Mortality in Older Age. JAMA
295: 190-198
[Abstract][Full Text]
Daviglus, M. L., Liu, K., Pirzada, A., Yan, L. L., Garside, D. B., Greenland, P., Manheim, L. M., Dyer, A. R., Wang, R., Lubitz, J., Manning, W. G., Fries, J. F., Stamler, J.
(2005). Cardiovascular Risk Profile Earlier in Life and Medicare Costs in the Last Year of Life. Arch Intern Med
165: 1028-1034
[Abstract][Full Text]
Liu, K., Dyer, A. R., Vu, T.-H., Pirzada, A., Manheim, L. M., Manning, W. G., Ashraf, M. S., Garside, D. B., Daviglus, M. L.
(2005). One-Hour Postload Plasma Glucose in Middle Age and Medicare Expenditures in Older Age Among Nondiabetic Men and Women: The Chicago Heart Association Detection Project in Industry. Diabetes Care
28: 1057-1062
[Abstract][Full Text]
Chen, W., Srinivasan, S. R., Li, S., Xu, J., Berenson, G. S.
(2005). Metabolic Syndrome Variables at Low Levels in Childhood Are Beneficially Associated With Adulthood Cardiovascular Risk: The Bogalusa Heart Study. Diabetes Care
28: 126-131
[Abstract][Full Text]
Daviglus, M. L., Liu, K., Yan, L. L., Pirzada, A., Manheim, L., Manning, W., Garside, D. B., Wang, R., Dyer, A. R., Greenland, P., Stamler, J.
(2004). Relation of Body Mass Index in Young Adulthood and Middle Age to Medicare Expenditures in Older Age. JAMA
292: 2743-2749
[Abstract][Full Text]
Daviglus, M. L., Liu, K.
(2004). Today's Agenda: We Must Focus on Achieving Favorable Levels of All Risk Factors Simultaneously. Arch Intern Med
164: 2086-2087
[Full Text]
Greenlund, K. J., Croft, J. B., Mensah, G. A.
(2004). Prevalence of Heart Disease and Stroke Risk Factors in Persons With Prehypertension in the United States, 1999-2000. Arch Intern Med
164: 2113-2118
[Abstract][Full Text]
Daviglus, M. L., Stamler, J., Pirzada, A., Yan, L. L., Garside, D. B., Liu, K., Wang, R., Dyer, A. R., Lloyd-Jones, D. M., Greenland, P.
(2004). Favorable Cardiovascular Risk Profile in Young Women and Long-term Risk of Cardiovascular and All-Cause Mortality. JAMA
292: 1588-1592
[Abstract][Full Text]
Greenlund, K. J., Zheng, Z. J., Keenan, N. L., Giles, W. H., Casper, M. L., Mensah, G. A., Croft, J. B.
(2004). Trends in Self-reported Multiple Cardiovascular Disease Risk Factors Among Adults in the United States, 1991-1999. Arch Intern Med
164: 181-188
[Abstract][Full Text]
Pirzada, A., Yan, L. L., Garside, D. B., Schiffer, L., Dyer, A. R., Daviglus, M. L.
(2004). Response Rates to a Questionnaire 26 Years after Baseline Examination with Minimal Interim Participant Contact and Baseline Differences between Respondents and Nonrespondents. Am J Epidemiol
159: 94-101
[Abstract][Full Text]
Daviglus, M. L., Liu, K., Yan, L. L., Pirzada, A., Garside, D. B., Schiffer, L., Dyer, A. R., Greenland, P., Stamler, J.
(2003). Body Mass Index in Middle Age and Health-Related Quality of Life in Older Age: The Chicago Heart Association Detection Project in Industry Study. Arch Intern Med
163: 2448-2455
[Abstract][Full Text]
Daviglus, M. L., Liu, K., Pirzada, A., Yan, L. L., Garside, D. B., Feinglass, J., Guralnik, J. M., Greenland, P., Stamler, J.
(2003). Favorable Cardiovascular Risk Profile in Middle Age and Health-Related Quality of Life in Older Age. Arch Intern Med
163: 2460-2468
[Abstract][Full Text]
Lubitz, J., Cai, L., Kramarow, E., Lentzner, H.
(2003). Health, Life Expectancy, and Health Care Spending among the Elderly. NEJM
349: 1048-1055
[Abstract][Full Text]
Wang, B. W. E., Ramey, D. R., Schettler, J. D., Hubert, H. B., Fries, J. F.
(2002). Postponed Development of Disability in Elderly Runners: A 13-Year Longitudinal Study. Arch Intern Med
162: 2285-2294
[Abstract][Full Text]
Kromhout, D., Menotti, A., Kesteloot, H., Sans, S.
(2002). Prevention of Coronary Heart Disease by Diet and Lifestyle: Evidence From Prospective Cross-Cultural, Cohort, and Intervention Studies. Circulation
105: 893-898
[Full Text]
Goldman, L., Phillips, K. A., Coxson, P., Goldman, P. A., Williams, L., Hunink, M. G. M., Weinstein, M. C.
(2001). The effect of risk factor reductions between 1981 and 1990 on coronary heart disease incidence, prevalence, mortality and cost. J Am Coll Cardiol
38: 1012-1017
[Abstract][Full Text]
Daviglus, M. L., Stamler, J.
(2001). Major risk factors and coronary heart disease: much has been achieved but crucial challenges remain. J Am Coll Cardiol
38: 1018-1022
[Full Text]
Singer, B. H., Manton, K. G.
(1998). The effects of health changes on projections of health service needs for the elderly population of the United States. Proc. Natl. Acad. Sci. USA
95: 15618-15622
[Abstract][Full Text]