FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |   Search Term  Advanced Search

Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe

Previous Volume 339:1156-1158 October 15, 1998 Number 16 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text Purchase this article Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited Related Article by Moreno-Reyes, R. PubMed Citation

Selenium, as selenocysteine, is an integral component of two important enzymes — glutathione peroxidase and iodothyronine deiodinase — that are present in many tissues, including the thyroid gland. Glutathione peroxidase catalyzes the breakdown of hydrogen peroxide, thereby protecting against oxidative damage. Iodothyronine deiodinase catalyzes the deiodination of thyroxine to triiodothyronine, a more potent thyroid hormone. Iodine is not an integral component of any enzyme, but it is an integral component of thyroxine and triiodothyronine. Selenium and iodine are thus linked biochemically because both are involved in thyroid hormone production.

Selenium and iodine are also linked geographically, most notably in Asia. . . . [Full Text of this Article]

References

HOME  |  SUBSCRIBE  |  SEARCH  |  CURRENT ISSUE  |  PAST ISSUES  |  COLLECTIONS  |  PRIVACY  |  TERMS OF USE  |  HELP  |  beta.nejm.org Comments and questions? Please contact us. The New England Journal of Medicine is owned, published, and copyrighted © 2009 Massachusetts Medical Society. All rights reserved.