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Previous Volume 339:1158-1160 October 15, 1998 Number 16 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Once viewed as an inevitable consequence of aging, cardiovascular disease is now known to be related to modifiable risk factors, especially smoking, elevated blood pressure, and elevated cholesterol. Numerous preventive interventions have been developed in recent decades to combat these risk factors. The issue now is how best to allocate resources among these interventions in order to prevent disease.

Antihypertensive drugs, for example, though effective, vary widely in their cost effectiveness. Propranolol costs $20,000 to save a year of life (life-year) for adults 35 to 64 years of age, and captopril costs $130,000¹ (the medical component of the Consumer Price . . . [Full Text of this Article]

References

This article has been cited by other articles:

• Tice, J. A., Ross, E., Coxson, P. G., Rosenberg, I., Weinstein, M. C., Hunink, M. G. M., Goldman, P. A., Williams, L., Goldman, L. (2001). Cost-effectiveness of Vitamin Therapy to Lower Plasma Homocysteine Levels for the Prevention of Coronary Heart Disease: Effect of Grain Fortification and Beyond. JAMA 286: 936-943 [Abstract] [Full Text]  
• Goldman, L., Coxson, P., Hunink, M. G. M., Goldman, P. A., Tosteson, A. N. A., Mittleman, M., Williams, L., Weinstein, M. C. (1999). The relative influence of secondary versus primary prevention using the National Cholesterol Education Program Adult Treatment Panel II guidelines. J Am Coll Cardiol 34: 768-776 [Abstract] [Full Text]  
• Redberg, R. F., Gaenzer, H., Neumayr, G., Patsch, J. R., Daviglus, M. L., Liu, K., Greenland, P., Stamler, J., Russell, L. B. (1999). Cardiovascular Risk Factors and Medicare Costs. NEJM 340: 813-814 [Full Text]  
• Rowe, J. W. (1999). Geriatrics, Prevention, and the Remodeling of Medicare. NEJM 340: 720-721 [Full Text]