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Correspondence
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Volume 339:1244-1246 October 22, 1998 Number 17
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Infection in Organ-Transplant Recipients

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 by Fishman, J. A.
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To the Editor: In the excellent review of infection in organ-transplant recipients by Fishman and Rubin (June 11 issue),1 we were surprised that human herpesvirus 6 (HHV-6) and herpesvirus 8 (HHV-8) infections were not addressed. HHV-8 is involved in the development of all forms of Kaposi's sarcoma; HHV-8 DNA has been found in nearly all Kaposi's sarcomas from transplant recipients who have been examined for it,2 and an angiogenesis-causing HHV-8 oncogene has been identified.3 This complication develops an average of 21 months after transplantation (so it would be included in the third period of the timetable proposed by the authors), . . . [Full Text of this Article]

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