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Previous Volume 339:1330-1331 October 29, 1998 Number 18 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text Purchase this article Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited Related Article by Brizel, D. M.

To the Editor: Brizel et al. (June 18 issue)¹ conclude that hyperfractionated irradiation with concurrent chemotherapy "is more efficacious and not more toxic than hyperfractionated irradiation alone." At three years, the estimated rate of overall survival was 55 percent in the combined-therapy group and 34 percent in the hyperfractionation group (P=0.07). This difference is not statistically significant.

Feeding tubes were required in 44 of 56 patients (79 percent) in the combined-treatment group and 29 of 60 patients (48 percent) in the hyperfractionation group. Soft-tissue necrosis occurred in 11 patients (20 percent) in the combined-treatment group and 7 patients (12 percent) . . . [Full Text of this Article]

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