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Previous Volume 339:115-117 July 9, 1998 Number 2 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Hyperglycemia is an important factor in the development and progression of the complications of diabetes mellitus. In this issue of the Journal, Fioretto et al. report that pancreas transplantation reverses the lesions of diabetic nephropathy in patients who have type 1 diabetes without uremia and who become normoglycemic after transplantation.¹ Successful transplantation of the pancreas (alone or in combination with a kidney) normalizes glucose homeostasis in patients with type 1 diabetes, but the effect of the graft on diabetic complications is variable.² It results in improvement in diabetic neuropathy but not diabetic retinopathy. The lack of improvement in retinopathy is . . . [Full Text of this Article]

References

This article has been cited by other articles:

• Schena, F. P., Gesualdo, L. (2005). Pathogenetic Mechanisms of Diabetic Nephropathy. J. Am. Soc. Nephrol. 16: S30-S33 [Abstract] [Full Text]  
• Maestroni, A., Ruggieri, D., Dell'Antonio, G., Luzi, L., Zerbini, G. (2005). C-peptide increases the expression of vasopressin-activated calcium-mobilizing receptor gene through a G protein-dependent pathway. Eur J Endocrinol 152: 135-141 [Abstract] [Full Text]  
• Venstrom, J. M., McBride, M. A., Rother, K. I., Hirshberg, B., Orchard, T. J., Harlan, D. M. (2003). Survival After Pancreas Transplantation in Patients With Diabetes and Preserved Kidney Function. JAMA 290: 2817-2823 [Abstract] [Full Text]  
• Luzi, L., Perseghin, G., Brendel, M. D., Terruzzi, I., Battezzati, A., Eckhard, M., Brandhorst, D., Brandhorst, H., Friemann, S., Socci, C., Carlo, V. D., Sereni, L. P., Benedini, S., Secchi, A., Pozza, G., Bretzel, R. G. (2001). Metabolic Effects of Restoring Partial {beta}-Cell Function After Islet Allotransplantation in Type 1 Diabetic Patients. Diabetes 50: 277-282 [Abstract] [Full Text]