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Correction to Adams et al., N Engl J Med 339(1):5-11 July 2, 1998.

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Volume 339:1477-1478 November 12, 1998 Number 20
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Prevention of Stroke by Transfusions in Children with Sickle Cell Anemia

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 by Adams, R. J.
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 by Adams, R. J.
To the Editor: The results of the carefully conducted study by Adams et al. (July 2 issue)1 of the value of transfusion in preventing strokes in children with sickle cell anemia and abnormal results on transcranial Doppler studies were impressive and promise to change approaches to the management of strokes in this disease. Adams et al. do not address the timing of the first transcranial Doppler study or the interval between studies. These important issues need to be addressed before a protocol based on transcranial Doppler ultrasonography can be universally applied.

A point requiring clarification is the total number of . . . [Full Text of this Article]

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