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Volume 339:1552-1553 November 19, 1998 Number 21
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Effects of Diet and Exercise on Cholesterol Levels

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 by Stefanick, M. L.
To the Editor: Stefanick et al. (July 2 issue) were unable to demonstrate a reduction in low-density lipoprotein (LDL) cholesterol levels with diet alone.1 We believe, however, that dietary intervention alone may be effective in lowering LDL cholesterol levels. The study by Stefanick et al. was well executed, and we commend the authors on their overall design. However, there are three methodologic issues that may have influenced their negative result.

First, the adherence of the study population to dietary recommendations was measured by means of two sets of five 24-hour dietary-recall questionnaires, the results of which were averaged, one at . . . [Full Text of this Article]

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