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Review Article
Current Concepts
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Volume 339:1828-1834 December 17, 1998 Number 25
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Primary Aldosteronism
Arunabha Ganguly, M.D.

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Primary aldosteronism resulting from an adrenocortical adenoma (aldosteronoma), as described by Conn,1 is one of a few potentially curable forms of hypertension. Aldosteronoma is the most common cause of primary aldosteronism. Aldosteronomas are usually small (less than 2 cm in diameter), are benign, and have a golden yellow color on their cut surfaces (Figure 1), with different adrenal-cell types visible on microscopy. Idiopathic aldosteronism, which is associated with bilateral micronodular or macronodular adrenal hyperplasia, constitutes 20 to 30 percent of cases of primary aldosteronism,2,3,4,5,6,7,8 although it is considered by some to be a variant of essential hypertension.9 Unilateral . . . [Full Text of this Article]

Pathophysiologic Changes in Aldosterone Secretion

Prevalence

Clinical Characteristics

Biochemical Findings

Screening

Diagnosis

Differential Diagnosis

Treatment


Source Information

From the Medical Service, James A. Haley Veterans Affairs Hospital and University of South Florida College of Medicine, Tampa.

Address reprint requests to Dr. Ganguly at the Veterans Affairs Hospital 111-M, 13000 Bruce B. Downs Blvd., Tampa, FL 33612.

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