Primary aldosteronism resulting from an adrenocortical adenoma(aldosteronoma), as described by Conn,1 is one of a few potentiallycurable forms of hypertension. Aldosteronoma is the most commoncause of primary aldosteronism. Aldosteronomas are usually small(less than 2 cm in diameter), are benign, and have a goldenyellow color on their cut surfaces (Figure 1), with differentadrenal-cell types visible on microscopy. Idiopathic aldosteronism,which is associated with bilateral micronodular or macronodularadrenal hyperplasia, constitutes 20 to 30 percent of cases ofprimary aldosteronism,2,3,4,5,6,7,8 although it is consideredby some to be a variant of essential hypertension.9 Unilateral. . . [Full Text of this Article]
Pathophysiologic Changes in Aldosterone Secretion
Prevalence
Clinical Characteristics
Biochemical Findings
Screening
Diagnosis
Differential Diagnosis
Treatment
Source Information
From the Medical Service, James A. Haley Veterans Affairs Hospital and University of South Florida College of Medicine, Tampa.
Address reprint requests to Dr. Ganguly at the Veterans Affairs Hospital 111-M, 13000 Bruce B. Downs Blvd., Tampa, FL 33612.
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