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Editorial
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Volume 339:1845-1846 December 17, 1998 Number 25
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Influenza Vaccination and the Guillain–Barré Syndrome

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 by Lasky, T.
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In about two thirds of cases, the immune neuropathy known as the Guillain–Barré syndrome is provoked by an acute infectious illness. In the autumn of 1976, there was an unexpected increase — by a factor of four to eight — in the number of cases of the Guillain–Barré syndrome after a government-sponsored mass-inoculation program in which 45 million adults in the United States received vaccine containing the A/New Jersey/76 influenzavirus (the "swine flu" virus).1 The increase in risk attributable to the vaccine was subsequently corroborated by a careful analysis of all cases of the Guillain–Barré syndrome that occurred in Michigan . . . [Full Text of this Article]

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