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Previous Volume 339:1846-1848 December 17, 1998 Number 25 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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The use of highly active antiretroviral therapy to control infection with human immunodeficiency virus type 1 (HIV-1) is in many ways a success story. Under optimal circumstances, combinations of drugs that inhibit the viral protease and reverse transcriptase suppress replication to below the limits of detection in the circulation. The production of the virus is stifled at its source in lymphatic tissues, and the large pools of virus stored in that reservoir are reduced to undetectable levels.^1,2 The control of viral replication benefits the ravaged immune system, even in the late stages of infection. The numbers of CD4+ T cells . . . [Full Text of this Article]

References

This article has been cited by other articles:

• Ewart, G. D., Nasr, N., Naif, H., Cox, G. B., Cunningham, A. L., Gage, P. W. (2004). Potential New Anti-Human Immunodeficiency Virus Type 1 Compounds Depress Virus Replication in Cultured Human Macrophages. Antimicrob. Agents Chemother. 48: 2325-2330 [Abstract] [Full Text]  
• Deora, A., Ratner, L. (2001). Viral Protein U (Vpu)-Mediated Enhancement of Human Immunodeficiency Virus Type 1 Particle Release Depends on the Rate of Cellular Proliferation. J. Virol. 75: 6714-6718 [Abstract] [Full Text]  
• Quinn, T. C., Wawer, M. J., Sewankambo, N., Serwadda, D., Li, C., Wabwire-Mangen, F., Meehan, M. O., Lutalo, T., Gray, R. H., The Rakai Project Study Group, (2000). Viral Load and Heterosexual Transmission of Human Immunodeficiency Virus Type 1. NEJM 342: 921-929 [Abstract] [Full Text]  
• (1998). In HIV Infection, ""Undetectable"" Is Still Infectious. JWatch General 1998: 1-1 [Full Text]