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Correspondence
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Volume 339:1858-1860 December 17, 1998 Number 25
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Prevention of Preterm Birth

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 by Goldenberg, R. L.
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To the Editor: Goldenberg and Rouse (July 30 issue)1 correctly emphasize the need to define further the causes of the preterm birth syndrome in order to identify, treat, and prevent implicated processes in susceptible mothers. The authors' failure to recognize the potential benefits and cost savings of applying our present knowledge leads to unjustified nihilism and clinical complacency. Lamentably, they ignore or give short shrift to biologically based approaches that have already been demonstrated to be effective in large controlled trials or that are founded on the molecular mechanisms of human parturition.

These increasingly appreciated approaches include avoidance of multifetal . . . [Full Text of this Article]

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