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Correspondence
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Volume 339:1944-1946 December 24, 1998 Number 26
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Loxoscelism

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 by Masters, E. J.
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To the Editor: Masters (Aug. 6 issue)1 provides a fascinating pictorial account of the progression of a lesion caused by the bite of a brown recluse spider, from the initial stages to healing. He reported that the patient was treated with dapsone. Dapsone, long used to reduce inflammation induced in treating leprosy, has been recommended for bites by brown recluse spiders because neutrophil infiltration is necessary for the development of necrotic lesions. Several studies have indicated that dapsone is an effective treatment for bites by brown recluse spiders.2,3,4 In my own work, I regularly discuss dapsone as a treatment option . . . [Full Text of this Article]

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