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Volume 339:196-199 July 16, 1998 Number 3
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Protective Ventilation for the Acute Respiratory Distress Syndrome

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 by Amato, M. B. P.
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 by Stewart, T. E.
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To the Editor: Experimental studies have provided unequivocal evidence that suboptimal patterns of mechanical ventilation can injure the lung.1 The studies of patients with the acute respiratory distress syndrome reported by Weg et al. and Stewart et al. (Feb. 5 issue)2,3 challenge this position. Another study reported in the same issue, by Amato et al.,4 suggests that a protective-ventilation strategy designed to minimize massive alveolar collapse and cyclic lung reopening and overdistention during mechanical ventilation improves the outcome.

We question the conclusions of Weg and coworkers. They conducted a retrospective analysis of data collected in a study designed to evaluate . . . [Full Text of this Article]

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