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Previous Volume 340:1081-1091 April 8, 1999 Number 14 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Since the performance of the first successful lung transplantation nearly two decades ago, the procedure has gained widespread acceptance as a therapeutic option for a diverse array of lung diseases. For patients with severe functional impairment and limited life expectancy, lung transplantation offers the possibility of a markedly improved quality of life and longer survival. Nonetheless, complications are frequent and result in constraints on long-term preservation of graft function and patient survival. This article will review the current status of lung transplantation, with particular attention to the selection of patients, achievable outcomes, and complications.

Recent Trends

After the initial technical successes of . . . [Full Text of this Article]

Timing of Referral

Selection of Appropriate Candidates

Allocation of Organs

Surgical Techniques

Immunosuppression

Outcomes

Survival

Pulmonary Function and Gas Exchange

Hemodynamics

Exercise Capacity

Quality of Life

Common Complications

Primary Graft Failure

Airway Complications

Infection

Rejection

            Acute Rejection

            Chronic Rejection

Future Directions

Source Information

From the Program for Advanced Lung Disease and Lung Transplantation, Pulmonary and Critical Care Division, University of Pennsylvania Medical Center, Philadelphia.

Address reprint requests to Dr. Kotloff at the Pulmonary and Critical Care Division, University of Pennsylvania Medical Center, 3400 Spruce St., Philadelphia, PA 19104, or at kotloff@mail.med.upenn.edu.

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