Lung Transplantation

doi:10.1056/NEJM199904083401406

Volume 340:1081-1091		April 8, 1999		Number 14

Lung Transplantation

Selim M. Arcasoy, M.D., and Robert M. Kotloff, M.D.

Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Since the performance of the first successful lung transplantationnearly two decades ago, the procedure has gained widespreadacceptance as a therapeutic option for a diverse array of lungdiseases. For patients with severe functional impairment andlimited life expectancy, lung transplantation offers the possibilityof a markedly improved quality of life and longer survival.Nonetheless, complications are frequent and result in constraintson long-term preservation of graft function and patient survival.This article will review the current status of lung transplantation,with particular attention to the selection of patients, achievableoutcomes, and complications.

Recent Trends

After the initial technical successes of . . . [Full Text of this Article]

Timing of Referral

Selection of Appropriate Candidates

Allocation of Organs

Surgical Techniques

Immunosuppression

Outcomes

Survival

Pulmonary Function and Gas Exchange

Hemodynamics

Exercise Capacity

Quality of Life

Common Complications

Primary Graft Failure

Airway Complications

Infection

Rejection

Acute Rejection

Chronic Rejection

Future Directions

Source Information

From the Program for Advanced Lung Disease and Lung Transplantation, Pulmonary and Critical Care Division, University of Pennsylvania Medical Center, Philadelphia.

Address reprint requests to Dr. Kotloff at the Pulmonary and Critical Care Division, University of Pennsylvania Medical Center, 3400 Spruce St., Philadelphia, PA 19104, or at kotloff@mail.med.upenn.edu.

References

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Mann, R., Nichols, J. (2009). Management of Chronic Obstructive Pulmonary Disease. AMERICAN JOURNAL OF LIFESTYLE MEDICINE 3: 458-465 [Abstract]
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Lee, J. C., Christie, J. D. (2009). Primary Graft Dysfunction. Proc Am Thorac Soc 6: 39-46 [Abstract] [Full Text]
Lyu, D. M., Zamora, M. R. (2009). Medical Complications of Lung Transplantation. Proc Am Thorac Soc 6: 101-107 [Abstract] [Full Text]
Levine, S. M. (2009). Lung Transplantation. ACCP Pulmonary Med Brd Rev 25: 563-584 [Full Text]
Shuhaiber, J. H., Kim, J. B., Hur, K., Gibbons, R. D. (2009). Survival of Primary and Repeat Lung Transplantation in the United States. Ann. Thorac. Surg. 87: 261-266 [Abstract] [Full Text]
Iwata, T., Philipovskiy, A., Fisher, A. J., Presson, R. G. Jr., Chiyo, M., Lee, J., Mickler, E., Smith, G. N., Petrache, I., Brand, D. B., Burlingham, W. J., Gopalakrishnan, B., Greenspan, D. S., Christie, J. D., Wilkes, D. S. (2008). Anti-Type V Collagen Humoral Immunity in Lung Transplant Primary Graft Dysfunction. J. Immunol. 181: 5738-5747 [Abstract] [Full Text]
Bankier, A. A., Mehrain, S., Kienzl, D., Weber, M., Estenne, M., Gevenois, P. A. (2008). Regional Heterogeneity of Air Trapping at Expiratory Thin-Section CT of Patients with Bronchiolitis: Potential Implications for Dose Reduction and CT Protocol Planning. Radiology 247: 862-870 [Abstract] [Full Text]
Thabut, G., Ravaud, P., Christie, J. D., Castier, Y., Fournier, M., Mal, H., Leseche, G., Porcher, R. (2008). Determinants of the Survival Benefit of Lung Transplantation in Patients with Chronic Obstructive Pulmonary Disease. Am. J. Respir. Crit. Care Med. 177: 1156-1163 [Abstract] [Full Text]
Kremer, T. M., Zwerdling, R. G., Michelson, P. H., O'Sullivan, B. P. (2008). Intensive Care Management of the Patient With Cystic Fibrosis. J Intensive Care Med 23: 159-177 [Abstract]
Davis, S. Q., Garrity, E. R. Jr (2007). Organ Allocation in Lung Transplant. Chest 132: 1646-1651 [Abstract] [Full Text]
Panoskaltsis-Mortari, A., Tram, K. V., Price, A. P., Wendt, C. H., Blazar, B. R. (2007). A New Murine Model for Bronchiolitis Obliterans Post Bone Marrow Transplant. Am. J. Respir. Crit. Care Med. 176: 713-723 [Abstract] [Full Text]
Harada, H., Lama, V. N., Badri, L. N., Ohtsuka, T., Petrovic-Djergovic, D., Liao, H., Yoshikawa, Y., Iwanaga, K., Lau, C. L., Pinsky, D. J. (2007). Early growth response gene-1 promotes airway allograft rejection. Am. J. Physiol. Lung Cell. Mol. Physiol. 293: L124-L130 [Abstract] [Full Text]
Yung, G. (2007). Lung Transplantation and Pulmonary Hypertension. SEMIN CARDIOTHORAC VASC ANESTH 11: 149-156 [Abstract]
Hadjiliadis, D. (2007). Special Considerations for Patients With Cystic Fibrosis Undergoing Lung Transplantation. Chest 131: 1224-1231 [Abstract] [Full Text]
Bankier, A. A., Schaefer-Prokop, C., De Maertelaer, V., Tack, D., Jaksch, P., Klepetko, W., Gevenois, P. A. (2007). Air Trapping: Comparison of Standard-Dose and Simulated Low-Dose Thin-Section CT Techniques. Radiology 242: 898-906 [Abstract] [Full Text]
McDyer, J. F. (2007). Human and Murine Obliterative Bronchiolitis in Transplant. Proc Am Thorac Soc 4: 37-43 [Abstract] [Full Text]
Keane, M. P., Gomperts, B. N., Weigt, S., Xue, Y. Y., Burdick, M. D., Nakamura, H., Zisman, D. A., Ardehali, A., Saggar, R., Lynch, J. P. III, Hogaboam, C., Kunkel, S. L., Lukacs, N. W., Ross, D. J., Grusby, M. J., Strieter, R. M., Belperio, J. A. (2007). IL-13 Is Pivotal in the Fibro-Obliterative Process of Bronchiolitis Obliterans Syndrome. J. Immunol. 178: 511-519 [Abstract] [Full Text]
Christie, J. D., Robinson, N., Ware, L. B., Plotnick, M., De Andrade, J., Lama, V., Milstone, A., Orens, J., Weinacker, A., Demissie, E., Bellamy, S., Kawut, S. M., for the Lung Transplant Outcomes Group, (2007). Association of Protein C and Type 1 Plasminogen Activator Inhibitor with Primary Graft Dysfunction. Am. J. Respir. Crit. Care Med. 175: 69-74 [Abstract] [Full Text]
Lu, B. S., Yu, A. D., Zhu, X., Garrity, E. R. Jr, Vigneswaran, W. T., Bhorade, S. M. (2006). Sequential gene expression profiling in lung transplant recipients with chronic rejection.. Chest 130: 847-854 [Abstract] [Full Text]
Medoff, B. D., Wain, J. C., Seung, E., Jackobek, R., Means, T. K., Ginns, L. C., Farber, J. M., Luster, A. D. (2006). CXCR3 and Its Ligands in a Murine Model of Obliterative Bronchiolitis: Regulation and Function.. J. Immunol. 176: 7087-7095 [Abstract] [Full Text]
Yip, N. H., Lederer, D. J., Kawut, S. M., Wilt, J. S., D'Ovidio, F., Wang, Y., Dwyer, E., Sonett, J. R., Arcasoy, S. M. (2006). Immunoglobulin G Levels before and after Lung Transplantation. Am. J. Respir. Crit. Care Med. 173: 917-921 [Abstract] [Full Text]
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Ben-Dor, I., Kramer, M. R., Raccah, A., Iakobishvilli, Z., Shitrit, D., Sahar, G., Hasdai, D. (2006). Echocardiography Versus Right-Sided Heart Catheterization Among Lung Transplantation Candidates. Ann. Thorac. Surg. 81: 1056-1060 [Abstract] [Full Text]
Liu, H., Liu, L., Fletcher, B. S., Visner, G. A. (2006). Novel Action of Indoleamine 2,3-Dioxygenase Attenuating Acute Lung Allograft Injury. Am. J. Respir. Crit. Care Med. 173: 566-572 [Abstract] [Full Text]
Dobbels, F, Verleden, G, Dupont, L, Vanhaecke, J, De Geest, S (2006). To transplant or not? The importance of psychosocial and behavioural factors before lung transplantation. Chronic Respiratory Disease 3: 39-47 [Abstract]
West, E. E., Lavoie, T. L., Orens, J. B., Chen, E. S., Ye, S. Q., Finkelman, F. D., Garcia, J. G. N., McDyer, J. F. (2006). Pluripotent Allospecific CD8+ Effector T Cells Traffic to Lung in Murine Obliterative Airway Disease. Am. J. Respir. Cell Mol. Bio. 34: 108-118 [Abstract] [Full Text]
Rosen, M. J. (2006). Cough in the Immunocompromised Host: ACCP Evidence-Based Clinical Practice Guidelines. Chest 129: 204S-205S [Abstract] [Full Text]
Forrest, I. A., Murphy, D. M., Ward, C., Jones, D., Johnson, G. E., Archer, L., Gould, F. K., Cawston, T. E., Lordan, J. L., Corris, P. A. (2005). Primary airway epithelial cell culture from lung transplant recipients. Eur Respir J 26: 1080-1085 [Abstract] [Full Text]
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Ben-Dor, I., Shitrit, D., Kramer, M. R., Iakobishvili, Z., Sahar, G., Hasdai, D. (2005). Is Routine Coronary Angiography and Revascularization Indicated Among Patients Undergoing Evaluation for Lung Transplantation?. Chest 128: 2557-2562 [Abstract] [Full Text]
Yates, B., Murphy, D. M., Forrest, I. A., Ward, C., Rutherford, R. M., Fisher, A. J., Lordan, J. L., Dark, J. H., Corris, P. A. (2005). Azithromycin Reverses Airflow Obstruction in Established Bronchiolitis Obliterans Syndrome. Am. J. Respir. Crit. Care Med. 172: 772-775 [Abstract] [Full Text]
Liu, H., Drew, P., Cheng, Y., Visner, G. A. (2005). Pirfenidone inhibits inflammatory responses and ameliorates allograft injury in a rat lung transplant model. J. Thorac. Cardiovasc. Surg. 130: 852-858 [Abstract] [Full Text]
Medoff, B. D., Seung, E., Wain, J. C., Means, T. K., Campanella, G. S.V., Islam, S. A., Thomas, S. Y., Ginns, L. C., Grabie, N., Lichtman, A. H., Tager, A. M., Luster, A. D. (2005). BLT1-mediated T cell trafficking is critical for rejection and obliterative bronchiolitis after lung transplantation. JEM 202: 97-110 [Abstract] [Full Text]
Christie, J. D., Kotloff, R. M., Ahya, V. N., Tino, G., Pochettino, A., Gaughan, C., DeMissie, E., Kimmel, S. E. (2005). The Effect of Primary Graft Dysfunction on Survival after Lung Transplantation. Am. J. Respir. Crit. Care Med. 171: 1312-1316 [Abstract] [Full Text]
Parekh, P. I., Blumenthal, J. A., Babyak, M. A., LaCaille, R., Rowe, S., Dancel, L., Carney, R. M., Davis, R. D., Palmer, S., for the INSPIRE Investigators, (2005). Gas Exchange and Exercise Capacity Affect Neurocognitive Performance in Patients With Lung Disease. Psychosom. Med. 67: 425-432 [Abstract] [Full Text]
Thabut, G., Mal, H., Cerrina, J., Dartevelle, P., Dromer, C., Velly, J.-F., Stern, M., Loirat, P., Leseche, G., Bertocchi, M., Mornex, J.-F., Haloun, A., Despins, P., Pison, C., Blin, D., Reynaud-Gaubert, M. (2005). Graft Ischemic Time and Outcome of Lung Transplantation: A Multicenter Analysis. Am. J. Respir. Crit. Care Med. 171: 786-791 [Abstract] [Full Text]
Bowdish, M. E., Pessotto, R., Barbers, R. G., Schenkel, F. A., Starnes, V. A., Barr, M. L. (2005). Long-term Pulmonary Function After Living-Donor Lobar Lung Transplantation in Adults. Ann. Thorac. Surg. 79: 418-425 [Abstract] [Full Text]
Christie, J. D., Sager, J. S., Kimmel, S. E., Ahya, V. N., Gaughan, C., Blumenthal, N. P., Kotloff, R. M. (2005). Impact of Primary Graft Failure on Outcomes Following Lung Transplantation. Chest 127: 161-165 [Abstract] [Full Text]
Tierney, A., Foster, R., Ogella, D. (2004). A perfusionist's role in lung transplant preservation. Perfusion 19: 351-357 [Abstract]
Post, M.C., Janssens, S., Van de Werf, F., Budts, W. (2004). Responsiveness to inhaled nitric oxide is a predictor for mid-term survival in adult patients with congenital heart defects and pulmonary arterial hypertension. Eur Heart J 25: 1651-1656 [Abstract] [Full Text]
Knollmann, F. D., Kapell, S., Lehmkuhl, H., Schulz, B., Bottcher, H., Hetzer, R., Felix, R. (2004). Dynamic High-Resolution Electron-Beam CT Scanning for the Diagnosis of Bronchiolitis Obliterans Syndrome After Lung Transplantation. Chest 126: 447-456 [Abstract] [Full Text]
Sutherland, E. R., Cherniack, R. M. (2004). Management of Chronic Obstructive Pulmonary Disease. NEJM 350: 2689-2697 [Full Text]
Abraham, D., Krenn, K., Seebacher, G., Paulus, P., Klepetko, W., Aharinejad, S. (2004). Upregulated hypoxia-inducible factor-1 DNA binding activity to the vascular endothelial growth factor-A promoter mediates increased vascular permeability in donor lung grafts. Ann. Thorac. Surg. 77: 1751-1755 [Abstract] [Full Text]
Konen, E., Gutierrez, C., Chaparro, C., Murray, C. P., Chung, T., Crossin, J., Hutcheon, M. A., Paul, N. S., Weisbrod, G. L. (2004). Bronchiolitis Obliterans Syndrome in Lung Transplant Recipients: Can Thin-Section CT Findings Predict Disease before Its Clinical Appearance?. Radiology 231: 467-473 [Abstract] [Full Text]
Hadjiliadis, D., Steele, M. P., Govert, J. A., Davis, R. D., Palmer, S. M. (2004). Outcome of Lung Transplant Patients Admitted to the Medical ICU. Chest 125: 1040-1045 [Abstract] [Full Text]
Ishii, M., Suzuki, Y., Takeshita, K., Miyao, N., Kudo, H., Hiraoka, R., Nishio, K., Sato, N., Naoki, K., Aoki, T., Yamaguchi, K. (2004). Inhibition of c-Jun NH2-Terminal Kinase Activity Improves Ischemia/Reperfusion Injury in Rat Lungs. J. Immunol. 172: 2569-2577 [Abstract] [Full Text]
Ardehali, A., Laks, H., Russell, H., Levine, M., Shpiner, R., Lackey, S., Ross, D. (2003). Modified reperfusion and ischemia-reperfusion injury in human lung transplantation. J. Thorac. Cardiovasc. Surg. 126: 1929-1934 [Abstract] [Full Text]
Ryu, J. H., Myers, J. L., Swensen, S. J. (2003). Bronchiolar Disorders. Am. J. Respir. Crit. Care Med. 168: 1277-1292 [Abstract] [Full Text]
Bankier, A. A., Van Muylem, A., Scillia, P., De Maertelaer, V., Estenne, M., Gevenois, P. A. (2003). Air Trapping in Heart-Lung Transplant Recipients: Variability of Anatomic Distribution and Extent at Sequential Expiratory Thin-Section CT. Radiology 229: 737-742 [Abstract] [Full Text]
Konen, E., Weisbrod, G. L., Pakhale, S., Chung, T., Paul, N. S., Hutcheon, M. A. (2003). Fibrosis of the Upper Lobes: A Newly Identified Late-Onset Complication After Lung Transplantation?. Am. J. Roentgenol. 181: 1539-1543 [Abstract] [Full Text]
de Perrot, M., Young, K., Imai, Y., Liu, M., Waddell, T. K., Fischer, S., Zhang, L., Keshavjee, S. (2003). Recipient T Cells Mediate Reperfusion Injury after Lung Transplantation in the Rat. J. Immunol. 171: 4995-5002 [Abstract] [Full Text]
Gimino, V. J., Lande, J. D., Berryman, T. R., King, R. A., Hertz, M. I. (2003). Gene Expression Profiling of Bronchoalveolar Lavage Cells in Acute Lung Rejection. Am. J. Respir. Crit. Care Med. 168: 1237-1242 [Abstract] [Full Text]
Sin, D. D., McAlister, F. A., Man, S. F. P., Anthonisen, N. R. (2003). Contemporary Management of Chronic Obstructive Pulmonary Disease: Scientific Review. JAMA 290: 2301-2312 [Abstract] [Full Text]
Glanville, A.R., Estenne, M. (2003). Indications, patient selection and timing of referral for lung transplantation. Eur Respir J 22: 845-852 [Abstract] [Full Text]
DeVito Dabbs, A., Hoffman, L. A., Iacono, A. T., Wells, C. L., Grgurich, W., Zullo, T. G., McCurry, K. R., Dauber, J. H. (2003). Pattern and Predictors of Early Rejection After Lung Transplantation. Am J Crit Care 12: 497-507 [Abstract] [Full Text]
Young, L. R., Hadjiliadis, D., Davis, R. D., Palmer, S. M. (2003). Lung Transplantation Exacerbates Gastroesophageal Reflux Disease. Chest 124: 1689-1693 [Abstract] [Full Text]
Belperio, J. A., Keane, M. P., Burdick, M. D., Lynch, J. P. III, Zisman, D. A., Xue, Y. Y., Li, K., Ardehali, A., Ross, D. J., Strieter, R. M. (2003). Role of CXCL9/CXCR3 Chemokine Biology during Pathogenesis of Acute Lung Allograft Rejection. J. Immunol. 171: 4844-4852 [Abstract] [Full Text]
Christie, J. D., Kotloff, R. M., Pochettino, A., Arcasoy, S. M., Rosengard, B. R., Landis, J. R., Kimmel, S. E. (2003). Clinical Risk Factors for Primary Graft Failure Following Lung Transplantation. Chest 124: 1232-1241 [Abstract] [Full Text]
Belperio, J. A. (2003). Paying a Toll for Acute Lung Allograft Rejection. Am. J. Respir. Crit. Care Med. 168: 623-624 [Full Text]
Kotloff, R. M. (2003). Lung Retransplantation: All for One or One for All?. Chest 123: 1781-1782 [Full Text]
Brugiere, O., Thabut, G., Castier, Y., Mal, H., Dauriat, G., Marceau, A., Leseche, G. (2003). Lung Retransplantation for Bronchiolitis Obliterans Syndrome: Long-term Follow-up in a Series of 15 Recipients. Chest 123: 1832-1837 [Abstract] [Full Text]
Knollmann, F. D., Ewert, R., Wundrich, T., Hetzer, R., Felix, R. (2002). Bronchiolitis Obliterans Syndrome in Lung Transplant Recipients: Use of Spirometrically Gated CT. Radiology 225: 655-662 [Abstract] [Full Text]
Hadjiliadis, D., Davis, R. D., Palmer, S. M. (2002). Is Transplant Operation Important in Determining Posttransplant Risk of Bronchiolitis Obliterans Syndrome in Lung Transplant Recipients?. Chest 122: 1168-1175 [Abstract] [Full Text]
Belperio, J. A., Keane, M. P., Burdick, M. D., Lynch, J. P. III, Xue, Y. Y., Li, K., Ross, D. J., Strieter, R. M. (2002). Critical Role for CXCR3 Chemokine Biology in the Pathogenesis of Bronchiolitis Obliterans Syndrome. J. Immunol. 169: 1037-1049 [Abstract] [Full Text]
Thabut, G., Vinatier, I., Stern, J.-B., Leseche, G., Loirat, P., Fournier, M., Mal, H. (2002). Primary Graft Failure Following Lung Transplantation* : Predictive Factors of Mortality. Chest 121: 1876-1882 [Abstract] [Full Text]
Barker, A. F. (2002). Bronchiectasis. NEJM 346: 1383-1393 [Full Text]
Hadjiliadis, D., Sporn, T. A., Perfect, J. R., Tapson, V. F., Davis, R. D., Palmer, S. M. (2002). Outcome of Lung Transplantation in Patients With Mycetomas. Chest 121: 128-134 [Abstract] [Full Text]
Salvatierra, A., Guerrero, R., Rodriguez, M., Alvarez, A., Soriano, F., Lopez-Pedrera, R., Ramirez, R., Carracedo, J., Lopez-Rubio, F., Lopez-Pujol, J., Velasco, F. (2001). Antithrombin III Prevents Early Pulmonary Dysfunction After Lung Transplantation in the Dog. Circulation 104: 2975-2980 [Abstract] [Full Text]
Haft, J. W., Montoya, P., Alnajjar, O., Posner, S. R., Bull, J. L., Iannettoni, M. D., Bartlett, R. H., Hirschl, R. B. (2001). An artificial lung reduces pulmonary impedance and improves right ventricular efficiency in pulmonary hypertension. J. Thorac. Cardiovasc. Surg. 122: 1094-1100 [Abstract] [Full Text]
THABUT, G., VINATIER, I., BRUGIERE, O., LESECHE, G., LOIRAT, P., BISSON, A., MARTY, J., FOURNIER, M., MAL, H. (2001). Influence of Preservation Solution on Early Graft Failure in Clinical Lung Transplantation. Am. J. Respir. Crit. Care Med. 164: 1204-1208 [Abstract] [Full Text]
Dupuis, R. E., Taber, D. J., Fann, A. L., Lumbert, K. P. (2001). Medical Management Considerations for Patients With Lung Transplantation. Journal of Pharmacy Practice 14: 258-276 [Abstract]
ABOYOUN, C. L., TAMM, M., CHHAJED, P. N., HOPKINS, P., MALOUF, M. A., RAINER, S., GLANVILLE, A. R. (2001). Diagnostic Value of Follow-up Transbronchial Lung Biopsy after Lung Rejection. Am. J. Respir. Crit. Care Med. 164: 460-463 [Abstract] [Full Text]
Siegel, M. J., Bhalla, S., Gutierrez, F. R., Hildebolt, C., Sweet, S. (2001). Post-Lung Transplantation Bronchiolitis Obliterans Syndrome: Usefulness of Expiratory Thin-Section CT for Diagnosis. Radiology 220: 455-462 [Abstract] [Full Text]
Stern, J.-B., Mal, H., Groussard, O., Brugiere, O., Marceau, A., Jebrak, G., Fournier, M. (2001). Prognosis of Patients With Advanced Idiopathic Pulmonary Fibrosis Requiring Mechanical Ventilation for Acute Respiratory Failure. Chest 120: 213-219 [Abstract] [Full Text]
Agostini, C., Calabrese, F., Rea, F., Facco, M., Tosoni, A., Loy, M., Binotto, G., Valente, M., Trentin, L., Semenzato, G. (2001). CXCR3 and Its Ligand CXCL10 Are Expressed by Inflammatory Cells Infiltrating Lung Allografts and Mediate Chemotaxis of T Cells at Sites of Rejection. Am. J. Pathol. 158: 1703-1711 [Abstract] [Full Text]
Crystal, R. G. (2001). Research Opportunities and Advances in Lung Disease. JAMA 285: 612-618 [Abstract] [Full Text]
Struber, M., Wilhelmi, M., Harringer, W., Niedermeyer, J., Anssar, M., Kunsebeck, A., Schmitto, J. D., Haverich, A. (2001). Flush perfusion with low potassium dextran solution improves early graft function in clinical lung transplantation. Eur. J. Cardiothorac. Surg. 19: 190-194 [Abstract] [Full Text]
Bankier, A. A., Van Muylem, A., Knoop, C., Estenne, M., Gevenois, P. A. (2001). Bronchiolitis Obliterans Syndrome in Heart-Lung Transplant Recipients: Diagnosis with Expiratory CT. Radiology 218: 533-539 [Abstract] [Full Text]
Villaran, Y., Sekela, M. E., Burki, N. K. (2001). Maximal Expiratory Flow Patterns After Single-Lung Transplantation in Patients With and Without Chronic Airways Obstruction. Chest 119: 163-168 [Abstract] [Full Text]
Phan, T. G., O'Neill, B. P., Kurtin, P. J. (2000). Posttransplant primary CNS lymphoma. Neuro Oncol Duke 2: 229-238 [Abstract]
ESTENNE, M., VAN MUYLEM, A., KNOOP, C., ANTOINE, M., the Brussels Lung Transplant Group, (2000). Detection of Obliterative Bronchiolitis after Lung Transplantation by Indexes of Ventilation Distribution. Am. J. Respir. Crit. Care Med. 162: 1047-1051 [Abstract] [Full Text]
Huang, Y.-C., Cheng, Y.-J., Lin, Y.-H., Wang, M.-J., Tsai, S.-K. (2000). Graft Failure Caused by Pulmonary Venous Obstruction Diagnosed by Intraoperative Transesophageal Echocardiography During Lung Transplantation. Anesth. Analg. 91: 558-560 [Abstract] [Full Text]
Gridelli, B., Remuzzi, G. (2000). Strategies for Making More Organs Available for Transplantation. NEJM 343: 404-410 [Full Text]
Lanuza, D. M., Lefaiver, C., Mc Cabe, M., Farcas, G. A., Garrity, E. Jr. (2000). Prospective Study of Functional Status and Quality of Life Before and After Lung Transplantation. Chest 118: 115-122 [Abstract] [Full Text]
(2000). Progressive breathlessness in an 18 year old male. Postgrad. Med. J. 76: 311-311 [Full Text]
Brickner, M. E., Hillis, L. D., Lange, R. A. (2000). Congenital Heart Disease in Adults- Second of Two Parts. NEJM 342: 334-342 [Full Text]
Mazariegos, G. V., Reyes, J. (1999). What's New in Pediatric Organ Transplantation. Pediatr. Rev. 20: 363-375 [Full Text]
Veyssier-Belot, C., Cacoub, P. (1999). Role of endothelial and smooth muscle cells in the physiopathology and treatment management of pulmonary hypertension. Cardiovasc Res 44: 274-282 [Abstract] [Full Text]

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