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Of Two Minds breaks new ground. The book's premise is that each hemisphere of the brain contains its own mind and its own distinct personality. In the normal person, the two hemispheres and their respective minds are in balance and interact harmoniously. However, when they are out of balance, mental illness may result, according to the book's author.
Schiffer's theory stems from his work with patients. He has observed that patients appear to be dominated by different personalities at different times sometimes by mature, reasonable, patient, self-confident personalities, and sometimes by insecure, anxious, self-denigrating, primitive personalities. The notion
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